Drug reference
Contraception ▶BY MOUTH ▶Females of childbearing potential: 1 active tablet daily for 24 days, followed by 1 inactive tablet daily for 4 days, to be started on day 1 of cycle with first active tablet (withdrawal bleeding occurs when inactive tablets being taken); subsequent courses repeated without interval
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→Appendix 1: combined hormonal contraceptives
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▶Common or very common Breast abnormalities. depression . menstrual cycle irregularities. mood altered. pelvic pain. sexual dysfunction ▶Uncommon Abdominal distension. appetite abnormal. galactorrhoea. hot flush. hyperhidrosis. oedema. painful sexual intercourse. seborrhoea. sensation of pressure. skin reactions. uterine cramps. vulvovaginal disorders ▶Rare or very rare Cerebrovascular insufficiency. concentration impaired. contact lens intolerance. dry eye . dry mouth. gallbladder disorders. hypertrichosis
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Toxicity in animal studies.
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Zoely ® (every day (ED) combined (monophasic) preparation), 1 active tablet daily for 24 days, followed by 1 inactive tablet daily for 4 days, starting on day 1 of cycle with first active tablet; subsequent courses repeated without interval (withdrawal bleeding occurs when inactive tablets being taken). Changing to Zoely ® Start the first active Zoely ® tablet on the day after taking the last active tablet of the previous brand or, at the latest, the day after the tablet-free or inactive tablet interval of the previous brand.
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There can be variation in the licensing of different medicines containing the same drug. Tablet ▶Zoely (Merck Sharp & Dohme Ltd) A Estradiol (as Estradiol hemihydrate) 1.5 mg, Nomegestrol acetate 2.5 mg Zoely 2.5mg/1.5mg tablets | 84 tablet P £19.80 DT = £19.80 eiiii F 840
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Diarrhoea and vomiting In cases of persistent vomiting or severe diarrhoea lasting more than 12 hours in women taking Zoely ®, refer to product literature. Missed doses A missed pill for a patient taking Zoely ® is one that is 12 hours or more late; for information on how to manage missed pills in women taking Zoely ®, refer to product literature.
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