Drug reference

isosorbide/hydralazine

Mosby’s 2024 Nursing Drug Reference

Source: Mosby’s 2024 Nursing Drug Reference
PDF pages: 729

Review source pages for extracted sections and age labels.

Overview

Names and pronunciation

(eye-soe-sor′bide/hye-dral′a-zeen) BiDil

PDF page 729

Functional class

Func. class.: Antihypertensive, vasodilator

PDF page 729

Uses

USES: Heart failure with reduced ejection fraction (HFrEF)

PDF page 729

Safety

Contraindications

CONTRAINDICATIONS Hypersensitivity to organic nitrates or any component; concomitant use with phos- phodiesterase 5 inhibitors (avanafil, sildenafil, tadalafil, vardenafil); concomi- tant use with riociguat

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Dose and formulations

Dosage and routes

DOSAGE AND ROUTES Heart failure with reduced ejection fraction (HFrEF) Adult: PO Initial: 1 tablet (20 mg iso- sorbide/37.5 mg hydralazine) 3 times daily; titrate dose in 2 to 4 wk to a max 2 tablets (total of 40 mg isosorbide/75 mg hydralazine) 3 times daily

PDF page 729

Available forms

Available forms: Tablet 20 mg/37.5 mg

PDF page 729

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

isosorbide/hydralazine

Mosby’s 2024 Nursing Drug Reference

Source: Mosby’s 2024 Nursing Drug Reference
PDF pages: 729

Review source pages for extracted sections and age labels.

Overview

Names and pronunciation

(eye-soe-sor′bide/hye-dral′a-zeen) BiDil

PDF page 729

Functional class

Func. class.: Antihypertensive, vasodilator

PDF page 729

Uses

USES: Heart failure with reduced ejection fraction (HFrEF)

PDF page 729

Safety

Contraindications

PDF page 729

Dose and formulations

Dosage and routes

PDF page 729

Available forms

Available forms: Tablet 20 mg/37.5 mg

PDF page 729

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.