Names and pronunciation
(la-mi′vyoo-deen/zye-doe′vyoo- deen) Combivir
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Drug reference
(la-mi′vyoo-deen/zye-doe′vyoo- deen) Combivir
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Func. class.: Antiretroviral, reverse transcriptase inhibitor, nucleoside
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USES: Treatment of HIV-1 infection in combination with other antiretrovirals
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CONTRAINDICATIONS: Hyper- sensitivity to lamivudine or zidovudine, or any component
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Black Box Warning: Bone marrow sup- pression, hepatitis B exacerbation, hepato- toxicity, lactic acidosis, myopathy
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DOSAGE AND ROUTES Adult: PO 1 tablet (lamivudine 150 mg/ zidovudine 300 mg) bid in combination with other antiretrovirals Children and adolescents weighing ≥30 kg: PO 1 tablet bid, use in combination with at least one other antiretroviral agent
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Available forms: Tabs 150 mg/300 mg
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