Drug reference

lomustine

Mosby’s 2024 Nursing Drug Reference

Source: Mosby’s 2024 Nursing Drug Reference
PDF pages: 808

Review source pages for extracted sections and age labels.

Overview

Names and pronunciation

(loe-mus′teen) Gleostine

PDF page 808

Functional class

Func. class.: Antineoplastic agent, alkylating agent (Nitrosourea)

PDF page 808

Uses

USES: Treatment of primary and metastatic brain tumors after appropriate surgical and/or radiotherapeutic treatment (in combination with other chemotherapy agents) of Hodgkin lymphoma that has progressed following initial chemotherapy

PDF page 808

Safety

Contraindications

CONTRAINDICATIONS Hyper- sensitivity to lomustine or any component

PDF page 808

Warnings and precautions

Black Box Warning: Severe leukopenia and/or thrombocytopenia, potential for overdose/poisoning

PDF page 808

Dose and formulations

Dosage and routes

DOSAGE AND ROUTES Adult/child: PO: 130 mg/m2 as a single dose q6wk; reduce dose to 100 mg/m2 as a single dose q6wk in patients with com- promised bone marrow function

PDF page 808

Available forms

Available forms: Capsules 5, 10, 40, 100 mg

PDF page 808

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

lomustine

Mosby’s 2024 Nursing Drug Reference

Source: Mosby’s 2024 Nursing Drug Reference
PDF pages: 808

Review source pages for extracted sections and age labels.

Overview

Names and pronunciation

(loe-mus′teen) Gleostine

PDF page 808

Functional class

Func. class.: Antineoplastic agent, alkylating agent (Nitrosourea)

PDF page 808

Uses

PDF page 808

Safety

Contraindications

CONTRAINDICATIONS Hyper- sensitivity to lomustine or any component

PDF page 808

Warnings and precautions

Black Box Warning: Severe leukopenia and/or thrombocytopenia, potential for overdose/poisoning

PDF page 808

Dose and formulations

Dosage and routes

DOSAGE AND ROUTES Adult/child: PO: 130 mg/m2 as a single dose q6wk; reduce dose to 100 mg/m2 as a single dose q6wk in patients with com- promised bone marrow function

PDF page 808

Available forms

Available forms: Capsules 5, 10, 40, 100 mg

PDF page 808

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.