Drug reference

lumacaftor/ivacaftor

Mosby’s 2024 Nursing Drug Reference

Source: Mosby’s 2024 Nursing Drug Reference
PDF pages: 820

Review source pages for extracted sections and age labels.

Overview

Names and pronunciation

(loo-ma-kaf′tor/eye-va-kaf′tor) Orkambi

PDF page 820

Functional class

Func. class.: Cystic fibrosis agent

PDF page 820

Uses

USES: Cystic fibrosis

PDF page 820

Safety

Contraindications

CONTRAINDICATIONS Hypersensitivity

PDF page 820

Dose and formulations

Dosage and routes

DOSAGE AND ROUTES Adult/child ≥12 yr: PO Lumacaftor 400 mg/ivacaftor 250 mg q12h Child ≥2 yr to 5 yr: PO: Weighing <14 kg: Lumacaftor 100 mg/ivacaftor 125-mg granule packet: 1 packet q12h; weighing ≥14 kg: Lumacaftor 150 mg/ivacaftor 188-mg granule packet: 1 packet q12h Child ≥6 yr to 11 yr: PO: Lumacaftor 100 mg/ivacaftor 125-mg tablets: 2 tablets q12h (lumacaftor 200 mg/ivacaftor 250 mg per dose)

PDF page 820

Available forms

Available forms: Tabs 100 mg/125 mg, 200 mg/125 mg; granules 100 mg/125 mg, 150 mg/188 mg

PDF page 820

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

lumacaftor/ivacaftor

Mosby’s 2024 Nursing Drug Reference

Source: Mosby’s 2024 Nursing Drug Reference
PDF pages: 820

Review source pages for extracted sections and age labels.

Overview

Names and pronunciation

(loo-ma-kaf′tor/eye-va-kaf′tor) Orkambi

PDF page 820

Functional class

Func. class.: Cystic fibrosis agent

PDF page 820

Uses

USES: Cystic fibrosis

PDF page 820

Safety

Contraindications

CONTRAINDICATIONS Hypersensitivity

PDF page 820

Dose and formulations

Dosage and routes

PDF page 820

Available forms

Available forms: Tabs 100 mg/125 mg, 200 mg/125 mg; granules 100 mg/125 mg, 150 mg/188 mg

PDF page 820

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.