Names and pronunciation
(om-bit′as-vir/par-i-ta′pre-vir/ri- toe′na-vir/da-sa′bue-vir) Viekira Pak, Viekira XR
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Drug reference
(om-bit′as-vir/par-i-ta′pre-vir/ri- toe′na-vir/da-sa′bue-vir) Viekira Pak, Viekira XR
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Func. class.: Antihepaciviral, NS3/4A protease inhibitor (anti-HCV)
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USES: Treatment of adults with chronic hepatitis C virus (HCV) infection genotype 1a without cirrhosis, in combi- nation with ribavirin, and genotype 1b without cirrhosis or with compensated cirrhosis
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Black Box Warning: Hepatitis B exac- erbation Chronic HCV genotype 1 infection (compensated cirrhosis with or without ribavirin) Adult: PO Immediate release (Viekira Pak): 2 tablets (ombitasvir 12.5 mg/pari- taprevir 75 mg/ritonavir 50 mg per tablet) every morning × 12 wk, dasabuvir tablet: 1 tablet (dasabuvir 250 mg) bid × 12 wk; extended release (Viekira XR): 3 tab- lets (ombitasvir 8.33 mg/paritaprevir 50 mg/ritonavir 33.33 mg/dasabuvir 200 mg per tablet) daily × 12 wk
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DOSAGE AND ROUTES
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Available forms: Tablet; extended- release tablet
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