Names and pronunciation
(pem′i-ga′ti-nib) Penazyre Func. class: Antineoplastic, fibroblast growth factor receptor (FGFR) inhibitor
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Drug reference
(pem′i-ga′ti-nib) Penazyre Func. class: Antineoplastic, fibroblast growth factor receptor (FGFR) inhibitor
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USES: Treatment of previously treated, unresectable, locally advanced/ metastatic cholangiocarcinoma with an FGFR 2 fusion or other rearrangement
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CONTRAINDICATIONS: Hypersensitivity, pregnancy, breastfeeding
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DOSAGE AND ROUTES Adult: PO: 13.5 mg daily on days 1-14 of a 21-day cycle; continue until disease progression or unacceptable toxicity See Appendix B PENICILLINS
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