Names and pronunciation
(proe′teen cee kon′suhn-trate) Ceprotin
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Drug reference
(proe′teen cee kon′suhn-trate) Ceprotin
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Func. class.: Blood product derivative
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USES: Prevention/treatment of venous thrombosis and purpura fulminans in severe congenital protein C deficiency
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CONTRAINDICATIONS None known
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DOSAGE AND ROUTES Severe congenital protein C deficiency Adult/child: IV: Acute episode/short-term prophylaxis: Initial dose: 100-120 units/kg; subsequent 3 doses: 60-80 units/kg q6hr (adjust to maintain peak protein C activity of 100%); maintenance dose: 45-60 units/ kg q6h or 12h (adjust to maintain recom- mended maintenance trough protein C ac- tivity levels >25%); long-term prophylaxis: maintenance dose: 45-60 units/kg q12h (recommended maintenance trough pro- tein C activity levels >25%)
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Available forms: Injection 500, 1000 IU/vial
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