Drug reference

pyrimethamine

Mosby’s 2024 Nursing Drug Reference

Source: Mosby’s 2024 Nursing Drug Reference
PDF pages: 1112

Review source pages for extracted sections and age labels.

Overview

Names and pronunciation

(peer-i-meth′a-meen) Daraprim

PDF page 1112

Functional class

Func. class.: Antimalarial

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Uses

USES: Treatment of toxoplasmosis (in combination with a sulfonamide)

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Safety

Contraindications

CONTRAINDICATIONS Hypersensitivity to pyrimethamine or any component, megaloblastic anemia due to folate deficiency

PDF page 1112

Dose and formulations

Dosage and routes

DOSAGE AND ROUTES Toxoplasmosis treatment. Adult: PO 50-75 mg/day × 1-3 wk depending then reduce dose by 50% and continue for 4-5 wk; use with a sulfonamide in combination with leucovorin

PDF page 1112

Available forms

Available forms: Tabs 25 mg

PDF page 1112

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

pyrimethamine

Mosby’s 2024 Nursing Drug Reference

Source: Mosby’s 2024 Nursing Drug Reference
PDF pages: 1112

Review source pages for extracted sections and age labels.

Overview

Names and pronunciation

(peer-i-meth′a-meen) Daraprim

PDF page 1112

Functional class

Func. class.: Antimalarial

PDF page 1112

Uses

USES: Treatment of toxoplasmosis (in combination with a sulfonamide)

PDF page 1112

Safety

Contraindications

CONTRAINDICATIONS Hypersensitivity to pyrimethamine or any component, megaloblastic anemia due to folate deficiency

PDF page 1112

Dose and formulations

Dosage and routes

DOSAGE AND ROUTES Toxoplasmosis treatment. Adult: PO 50-75 mg/day × 1-3 wk depending then reduce dose by 50% and continue for 4-5 wk; use with a sulfonamide in combination with leucovorin

PDF page 1112

Available forms

Available forms: Tabs 25 mg

PDF page 1112

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.