Therapeutic Action
Antibacterial (sulfonamide group)
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Drug reference
Antibacterial (sulfonamide group)
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Prophylaxis and treatment of infections of in severe burns Treatment of infections in leg ulcers
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Child 2 months and over and adult: clean the wound then apply a 3 to 5 mm layer of silver sulfadiazine cream to the wound once daily and cover with sterile compresses.
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Do not use in patients with allergy to sulfonamides; in children under 2 months. Do not apply other topical treatments to wounds where silver sulfadiazine is applied. Use with caution in children under 2 years (risk of systemic absorption); in patients with severe renal or hepatic impairment. May cause: skin reactions, grey skin discoloration, skin photosensitivity; rarely: allergic reactions, sometimes severe (Lyell’s and Stevens-Johnson syndromes). systemic adverse effects related to sulfonamides (haematological, renal, cutaneous disorders, etc.) when applied to a large surface area, mucous membranes or prolonged use. rd Pregnancy: avoid if possible during the 3 trimester of pregnancy (risk of jaundice in the neonate) Breast-feeding: CONTRA-INDICATED if the child is under one month
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1% sterile cream, tube or jar
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Until wound has healed or until skin graft, when required.
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– Between 8 °C and 25 °C After use, keep the tube or jar tightly closed to avoid exposure to light.
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