Names and pronunciation
(thye-oh-tep′a) Tepadina
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Drug reference
(thye-oh-tep′a) Tepadina
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Func. class.: Antineoplastic, alkylating agent
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USES: To reduce the risk of graft rejection when used with busulfan and cyclophosphamide as a preparative regimen for allogeneic hematopoietic progenitor (stem) cell transplantation in children with class 3 beta-thalassemia
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CONTRAINDICATIONS Hypersensitivity, use with live/attenuated vaccines
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DOSAGE AND ROUTES Child: IV: 5 mg/kg IV over 3 hours (via a central venous catheter) approximately 12 hours apart for 2 doses on day -6 prior to an allogeneic hematopoietic progenitor cell transplantation (HSCT) in combination with high-dose busulfan and cyclophospha- mide
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Available forms: Injection 15 mg
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