Individual generic drug information

valsartan

Reference monograph

Part of registered formulation

AMLODIPINE + VALSARTAN + HYDROCHLOROT HIAZIDE

Reference record: Valsartan
Source: BNF 80 (2020–2021)
Printed source pages: 212, 213
Age groups indexed: 1

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Valsartan only.

Indications And Dose

Hypertension ▶BY MOUTH ▶Adult: Initially 80 mg once daily, increased if necessary up to 320 mg daily, doses to be increased at intervals of 4 weeks Hypertension with intravascular volume depletion ▶BY MOUTH ▶Adult: Initially 40 mg once daily, increased if necessary up to 320 mg daily, doses to be increased at intervals of 4 weeks Heart failure when ACE inhibitors cannot be used, or in conjunction with an ACE inhibitor when a beta-blocker cannot be used | Heart failure, in conjunction with an ACE inhibitor when a beta-blocker cannot be used (under expert supervision) ▶BY MOUTH ▶Adult: Initially 40 mg twice daily, increased to up to 160 mg twice daily, doses to be increased at intervals of at least 2 weeks Myocardial infarction with left ventricular failure or left ventricular systolic dysfunction (adjunct) ▶BY MOUTH ▶Adult: Initially 20 mg twice daily, increased if necessary up to 160 mg twice daily, doses to be increased over several weeks if tolerated

Source page 212

Contra Indications

Biliary cirrhosis. cholestasis

Source page 212

Safety

Extracted information for Valsartan only.

Interactions

→Appendix 1: angiotensin-II receptor antagonists

Source page 212

Side Effects

▶Uncommon Heart failure. syncope ▶Frequency not known Neutropenia. serum sickness. vasculitis

Source page 212

Hepatic Impairment

Dose adjustments Manufacturer advises maximum 80 mg daily in mild to moderate impairment.

Source page 212

Renal Impairment

Use with caution if eGFR less than 10 mL/minute/1.73 m2—no information available.

Source page 212

Dose and formulations

Extracted information for Valsartan only.

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: oral suspension, oral solution Oral solution ▶Diovan (Novartis Pharmaceuticals UK Ltd) Valsartan 3 mg per 1 ml Diovan 3mg/1ml oral solution | 160 ml P £7.20 DT = £7.20 Tablet ▶Valsartan (Non-proprietary) Valsartan 40 mg Valsartan 40mg tablets | 7 tablet P £7.87 DT = £7.84 Valsartan 160 mg Valsartan 160mg tablets | 28 tablet P £14.69 DT = £14.69 Valsartan 320 mg Valsartan 320mg tablets | 28 tablet P £20.23 DT = £18.18 Capsule ▶Valsartan (Non-proprietary) Valsartan 40 mg Valsartan 40mg capsules | 28 capsule P £13.97 DT = £5.54 Valsartan 80 mg Valsartan 80mg capsules | 28 capsule P £14.35 DT = £9.48 Valsartan 160 mg Valsartan 160mg capsules | 28 capsule P £18.41 DT = £12.76 Combinations available: Amlodipine with valsartan, p. 169

Source pages 212, 213

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Adults

First line only; read the complete Indications and dose section above.

Initially 80 mg once daily, increased if necessary

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 212

Adults

First line only; read the complete Indications and dose section above.

Initially 40 mg once daily, increased if necessary

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 212

Adults

First line only; read the complete Indications and dose section above.

Initially 40 mg twice daily, increased to up to

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 212

Adults

First line only; read the complete Indications and dose section above.

Initially 20 mg twice daily, increased if necessary

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 212

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.

Individual generic drug information

valsartan

Reference monograph

Part of registered formulation

AMLODIPINE + VALSARTAN + HYDROCHLOROT HIAZIDE

Reference record: Valsartan
Source: BNF 80 (2020–2021)
Printed source pages: 212, 213
Age groups indexed: 1

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Valsartan only.

Indications And Dose

Source page 212

Contra Indications

Biliary cirrhosis. cholestasis

Source page 212

Safety

Extracted information for Valsartan only.

Interactions

→Appendix 1: angiotensin-II receptor antagonists

Source page 212

Side Effects

▶Uncommon Heart failure. syncope ▶Frequency not known Neutropenia. serum sickness. vasculitis

Source page 212

Hepatic Impairment

Dose adjustments Manufacturer advises maximum 80 mg daily in mild to moderate impairment.

Source page 212

Renal Impairment

Use with caution if eGFR less than 10 mL/minute/1.73 m2—no information available.

Source page 212

Dose and formulations

Extracted information for Valsartan only.

Medicinal Forms

Source pages 212, 213

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Adults

First line only; read the complete Indications and dose section above.

Initially 80 mg once daily, increased if necessary

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 212

Adults

First line only; read the complete Indications and dose section above.

Initially 40 mg once daily, increased if necessary

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 212

Adults

First line only; read the complete Indications and dose section above.

Initially 40 mg twice daily, increased to up to

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 212

Adults

First line only; read the complete Indications and dose section above.

Initially 20 mg twice daily, increased if necessary

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 212

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.