Therapeutic Action
Antiretroviral, HIV protease inhibitor
Source page 49
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Individual generic drug information
Extracted information for ATAZANAVIR only.
Antiretroviral, HIV protease inhibitor
Source page 49
HIV infection, in combination with ritonavir (booster) and other antiretrovirals
Source page 49
Extracted information for ATAZANAVIR only.
Do not administer to patients with severe hepatic impairment. Administer with caution and monitor use in patients with haemophilia (increased bleeding) or mild to moderate hepatic impairment. May cause: jaundice, gastrointestinal disturbances, headache, insomnia, fatigue, peripheral neuropathy, asymptomatic hyperbilirubinaemia, cholelithiasis, urolithiasis, conduction disorders, hyperglycaemia, hyperlipidaemia, lipodystrophy; skin rash sometimes severe, hepatic disorders; in this event, stop treatment immediately. Do not combine with rifampicin or omeprazole (decreased plasma concentrations of atazanavir): replace rifampicin with rifabutin; if omeprazole is necessary, do not exceed 20 mg daily and take each drug 12 hours apart. Administer with caution and monitor combination with drugs that prolong the QT interval (amiodarone, co-artemether, mefloquine, quinine, haloperidol, etc.). Do not administer simultaneously with antacids containing aluminium or magnesium hydroxide. Take 2 hours apart. Atazanavir in combination with ritonavir reduces the efficacy of implants and oral contraceptives: use injectable medroxyprogesterone or an intrauterine device or an oral contraceptive containing at least 30 micrograms of ethinylestradiol per tablet. Pregnancy: no contra-indication; monitor bilirubin levels and/or signs of jaundice in neonates.
Source pages 49, 50
Extracted information for ATAZANAVIR only.
200 mg capsule 300 mg atazanavir/100 mg ritonavir tablet
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Child 10 to < 25 kg: one 200 mg capsule once daily (+ 100 mg ritonavir once daily) Child ≥ 25 kg and adult: one 300 mg/100 mg tablet once daily
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Depending on the efficacy and tolerance of atazanavir and ritonavir.
Source page 49
Extracted information for ATAZANAVIR only.
Take with meals together with ritonavir. Do not open the capsules. Also comes in 100 mg, 150 mg and 300 mg capsules, not in combination with ritonavir.
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– Below 25 °C
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Filter the extracted dose blocks for this individual drug.
one 300 mg/100 mg tablet once daily
Candidate age grouping · source page 49