Individual generic drug information
Extracted information for Brinzolamide only.
Reduction of intra-ocular pressure in ocular hypertension and open-angle glaucoma either as adjunct to beta- blockers or prostaglandin analogues or used alone in patients unresponsive to beta-blockers or if beta- blockers contra-indicated Eye ▶TO THE EYE ▶Adult: Apply twice daily, then increased if necessary up to 3 times a day
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Hyperchloraemic acidosis
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Renal tubular immaturity or abnormality—risk of metabolic acidosis. systemic absorption follows topical application
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Contra-indicated if history of sulfonamide hypersensitivity.
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Extracted information for Brinzolamide only.
→Appendix 1: brinzolamide
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▶Common or very common Eye discomfort. eye disorders. taste altered. vision disorders ▶Uncommon Arrhythmias. asthenia. cardio-respiratory distress. chest discomfort. cough. depression. diarrhoea. dizziness. dry eye. dry mouth. dyspnoea. epistaxis. eye deposit. eye inflammation. feeling abnormal. foreign body in eye. gastrointestinal discomfort. gastrointestinal disorders. headache. increased risk of infection. memory loss. motor dysfunction. muscle complaints. nasal complaints. nausea. nervousness. oral disorders. oropharyngeal pain. pain. palpitations. renal pain. scleral discolouration. sensation abnormal. sexual dysfunction. skin reactions. sleep disorders. throat complaints. vomiting ▶Rare or very rare Alopecia. angina pectoris. drowsiness. irritability. optic nerve disorder. respiratory disorders. tinnitus ▶Frequency not known Appetite decreased. arthralgia. asthma. hypertension. malaise. peripheral oedema. tremor. urinary frequency increased. vertigo SIDE-EFFECTS, FURTHER INFORMATION Systemic absorption can rarely cause sulfonamide-like side-effects and may require discontinuation if severe.
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Avoid—toxicity in animal studies.
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Use only if benefit outweighs risk.
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Manufacturer advises avoid—no information available.
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Avoid if eGFR less than 30 mL/minute/1.73 m2.
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Extracted information for Brinzolamide only.
There can be variation in the licensing of different medicines containing the same drug. Eye drops EXCIPIENTS: May contain Benzalkonium chloride, disodium edetate ▶Brinzolamide (Non-proprietary) Brinzolamide 10 mg per 1 ml Brinzolamide 10mg/ml eye drops | 5 ml P £6.92 DT = £3.03 ▶Azopt (Novartis Pharmaceuticals UK Ltd) Brinzolamide 10 mg per 1 ml Azopt 10mg/ml eye drops | 5 ml P £6.92 DT = £3.03
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Filter the extracted dose blocks for this individual drug.
First line only; read the complete Indications and dose section above.
Apply twice daily, then increased if necessary up
This is a first-line fragment. Read the full Indications and Dose section above.
Candidate age grouping · source page 1267
