Individual generic drug information

dorzolamide

Reference monograph

Part of registered formulation

DORZOLAMIDE HYDROCHLORIDE

Reference record: Dorzolamide
Source: BNF 80 (2020–2021)
Printed source pages: 1268
Age groups indexed: 1

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Dorzolamide only.

Indications And Dose

Raised intra-ocular pressure in ocular hypertension used alone in patients unresponsive to beta-blockers or if beta-blockers contra-indicated | Open-angle glaucoma used alone in patients unresponsive to beta-blockers or if beta-blockers contra-indicated | Pseudo-exfoliative glaucoma used alone in patients unresponsive to beta- blockers or if beta-blockers contra-indicated ▶TO THE EYE ▶Adult: Apply 3 times a day Raised intra-ocular pressure in ocular hypertension as adjunct to beta-blocker | Open-angle glaucoma as adjunct to beta-blocker | Pseudo-exfoliative glaucoma as adjunct to beta-blocker ▶TO THE EYE ▶Adult: Apply twice daily

Source page 1268

Contra Indications

Hyperchloraemic acidosis

Source page 1268

Cautions

Chronic corneal defects. history of intra-ocular surgery. history of renal calculi. low endothelial cell count . systemic absorption follows topical application

Source page 1268

Allergy And Cross Sensitivity

Contra-indicated if history of sulfonamide hypersensitivity.

Source page 1268

Prescribing And Dispensing Information

Although multi-dose dorzolamide eye drops commonly contain preservatives, preservative-free unit dose vials may be available.

Source page 1268

Safety

Extracted information for Dorzolamide only.

Interactions

→Appendix 1: dorzolamide

Source page 1268

Side Effects

▶Common or very common Asthenia. eye discomfort. eye disorders. eye inﬂammation. headache. nausea. paraesthesia. taste bitter. vision disorders ▶Rare or very rare Angioedema. bronchospasm. dizziness. dry mouth. dyspnoea. epistaxis. local reaction. pain. severe cutaneous adverse reactions (SCARs). skin reactions. throat irritation. urolithiasis SIDE-EFFECTS, FURTHER INFORMATION Systemic absorption can cause sulfonamide-like side-effects and may require discontinuation if severe.

Source page 1268

Pregnancy

Manufacturer advises avoid—toxicity in animal studies.

Source page 1268

Breast Feeding

Manufacturer advises avoid—no information available.

Source page 1268

Hepatic Impairment

Manufacturer advises caution—no information available.

Source page 1268

Renal Impairment

Avoid if eGFR less than 30 mL/minute/1.73 m2.

Source page 1268

Dose and formulations

Extracted information for Dorzolamide only.

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Eye drops EXCIPIENTS: May contain Benzalkonium chloride ▶Dorzolamide (Non-proprietary) Dorzolamide (as Dorzolamide hydrochloride) 20 mg per 1 ml Dorzolamide 20mg/ml eye drops | 5 ml P £5.69 DT = £2.46 ▶Eydelto (Aspire Pharma Ltd) Dorzolamide (as Dorzolamide hydrochloride) 20 mg per 1 ml Eydelto 20mg/ml eye drops | 5 ml P £12.09 DT = £12.09 ▶Trusopt (Santen UK Ltd) Dorzolamide (as Dorzolamide hydrochloride) 20 mg per 1 ml Trusopt 20mg/ml eye drops 0.2ml unit dose preservative free | 60 unit dose P £24.18 DT = £24.18 Trusopt 20mg/ml eye drops | 5 ml P £6.33 DT = £2.46

Source page 1268

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Adults

First line only; read the complete Indications and dose section above.

Apply 3 times a day

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1268

Adults

First line only; read the complete Indications and dose section above.

Apply twice daily

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1268

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.

Individual generic drug information

dorzolamide

Reference monograph

Part of registered formulation

DORZOLAMIDE HYDROCHLORIDE

Reference record: Dorzolamide
Source: BNF 80 (2020–2021)
Printed source pages: 1268
Age groups indexed: 1

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Dorzolamide only.

Indications And Dose

Source page 1268

Contra Indications

Hyperchloraemic acidosis

Source page 1268

Cautions

Chronic corneal defects. history of intra-ocular surgery. history of renal calculi. low endothelial cell count . systemic absorption follows topical application

Source page 1268

Allergy And Cross Sensitivity

Contra-indicated if history of sulfonamide hypersensitivity.

Source page 1268

Prescribing And Dispensing Information

Although multi-dose dorzolamide eye drops commonly contain preservatives, preservative-free unit dose vials may be available.

Source page 1268

Safety

Extracted information for Dorzolamide only.

Interactions

→Appendix 1: dorzolamide

Source page 1268

Side Effects

Source page 1268

Pregnancy

Manufacturer advises avoid—toxicity in animal studies.

Source page 1268

Breast Feeding

Manufacturer advises avoid—no information available.

Source page 1268

Hepatic Impairment

Manufacturer advises caution—no information available.

Source page 1268

Renal Impairment

Avoid if eGFR less than 30 mL/minute/1.73 m2.

Source page 1268

Dose and formulations

Extracted information for Dorzolamide only.

Medicinal Forms

Source page 1268

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Adults

First line only; read the complete Indications and dose section above.

Apply 3 times a day

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1268

Adults

First line only; read the complete Indications and dose section above.

Apply twice daily

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1268

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.