Individual generic drug information
Extracted information for Flupentixol decanoate only.
Maintenance in schizophrenia and other psychoses ▶BY DEEP INTRAMUSCULAR INJECTION ▶Adult: Test dose 20 mg, dose to be injected into the upper outer buttock or lateral thigh, then 20–40 mg after at least 7 days, then 20–40 mg every 2–4 weeks, adjusted according to response, usual maintenance dose 50 mg every 4 weeks to 300 mg every 2 weeks; maximum 400 mg per week ▶Elderly: Dose is initially quarter to half adult dose
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Children. CNS depression. comatose states. excitable patients. overactive patients
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An alternative antipsychotic may be necessary if symptoms such as aggression or agitation appear. hyperthyroidism. hypothyroidism. phaeochromocytoma. when transferring from oral to depot therapy, the dose by mouth should be reduced gradually
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Extracted information for Flupentixol decanoate only.
→Appendix 1: flupentixol
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▶Common or very common Appetite abnormal. asthenia. concentration impaired. depression. diarrhoea. dyspnoea . gastrointestinal discomfort. headache. hyperhidrosis. hypersalivation. muscle complaints. nervousness. palpitations. sexual dysfunction. skin reactions. urinary disorder. vision disorders ▶Uncommon Confusion. flatulence. hot flush. nausea. oculogyration. photosensitivity reaction. speech disorder ▶Rare or very rare Glucose tolerance impaired. hyperglycaemia. jaundice. thrombocytopenia ▶Frequency not known Suicidal tendencies SIDE-EFFECTS, FURTHER INFORMATION Side-effects may persist until the drug has been cleared from its depot site.
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Manufacturer advises caution— monitor serum drug concentration. Dose adjustments Manufacturer advises initiate at low dose orally to check for tolerability before switching to depot formulation.
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Dose adjustments Start with small doses in severe renal impairment because of increased cerebral sensitivity.
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Treatment requires careful monitoring for optimum effect.
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Extracted information for Flupentixol decanoate only.
In general not more than 2–3mL of oily injection should be administered at any one site. Correct injection technique (including use of z-track technique) and rotation of injection sites are essential. When initiating therapy with sustained-release preparations of conventional antipsychotics, patients should first be given a small test-dose as undesirable side- effects are prolonged.
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There can be variation in the licensing of different medicines containing the same drug. Solution for injection ▶Depixol (Lundbeck Ltd) Flupentixol decanoate 20 mg per 1 ml Depixol 40mg/2ml solution for injection ampoules | 10 ampoule P £25.39 DT = £25.39 Depixol 20mg/1ml solution for injection ampoules | 10 ampoule P £15.17 DT = £15.17 Flupentixol decanoate 100 mg per 1 ml Depixol Conc 100mg/1ml solution for injection ampoules | 10 ampoule P £62.51 DT = £62.51 Flupentixol decanoate 200 mg per 1 ml Depixol Low Volume 200mg/1ml solution for injection ampoules | 5 ampoule P £97.59 DT = £97.59 ▶Psytixol (Mylan) Flupentixol decanoate 20 mg per 1 ml Psytixol 40mg/2ml solution for injection ampoules | 10 ampoule P £25.38 DT = £25.39 Psytixol 20mg/1ml solution for injection ampoules | 10 ampoule P £15.16 DT = £15.17 Flupentixol decanoate 100 mg per 1 ml Psytixol 50mg/0.5ml solution for injection ampoules | 10 ampoule P £34.12 DT = £34.12 Psytixol 100mg/1ml solution for injection ampoules | 10 ampoule P £62.50 DT = £62.51 Flupentixol decanoate 200 mg per 1 ml Psytixol 200mg/1ml solution for injection ampoules | 5 ampoule P £97.58 DT = £97.59 eiiii F 401
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Filter the extracted dose blocks for this individual drug.
First line only; read the complete Indications and dose section above.
Test dose 20 mg, dose to be injected into the
This is a first-line fragment. Read the full Indications and Dose section above.
Candidate age grouping · source page 432
