Indications And Dose
Establish presence of gestational diabetes ▶BY MOUTH ▶Adult: Test dose 75 g, anhydrous glucose to be given to the fasting patient and blood-glucose concentrations measured at intervals, to be given with 200–300 mL fluid Oral glucose tolerance test ▶BY MOUTH ▶Adult: Test dose 75 g, anhydrous glucose to be given to the fasting patient and blood-glucose concentrations measured at intervals, to be given with 200–300 mL fluid Hypoglycaemia ▶BY INTRAVENOUS INFUSION ▶Child: 500 mg/kg, to be administered as Glucose 10% intravenous infusion into a large vein through a large- gauge needle; care is required since this concentration is irritant ▶Adult: 15–20 g, to be administered over 15 minutes as Glucose 10% or 20% intravenous infusion into a large vein through a large-gauge needle; care is required since these concentrations are irritant Energy source ▶BY INTRAVENOUS INFUSION ▶Adult: 1–3 litres daily, solution concentration of 20–50% to be administered Water replacement ▶BY INTRAVENOUS INFUSION ▶Adult: The volume of glucose solution needed to replace deficits may vary (consult product literature) Persistent cyanosis (in combination with propranolol) when blood glucose less than 3 mmol/litre (followed by morphine) ▶BY INTRAVENOUS INFUSION ▶Child: 200 mg/kg, to be administered as Glucose 10% intravenous infusion over 10 minutes Management of diabetic ketoacidosis ▶BY INTRAVENOUS INFUSION ▶Child: Glucose 5% or 10% should be added to replacement fluid once blood-glucose concentration falls below 14 mmol/litre ▶Adult: Glucose 10% should be given once blood- glucose concentration falls below 14 mmol/litre, to be administered into a large vein through a large-gauge needle at a rate of 125 mL/hour, in addition to the sodium chloride 0.9% infusion DOSE EQUIVALENCE AND CONVERSION ▶75 g anhydrous glucose is equivalent to Glucose BP 82.5 g.
Source pages 1124, 1125