Therapeutic Action
Osmotic laxative
Source page 187
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Individual generic drug information
Extracted information for LACTULOSE only.
Osmotic laxative
Source page 187
Prevention of constipation in patients taking opioid analgesics (e.g. codeine, morphine)
Source page 187
Extracted information for LACTULOSE only.
Do not administer to patients with Crohn’s disease, ulcerative colitis, intestinal obstruction, undiagnosed abdominal pain. May cause: abdominal discomfort, flatulence and diarrhoea. In the event of diarrhoea, exclude a faecal impaction and intestinal obstruction; reduce the dose. Pregnancy: no contra-indication Breast-feeding: no contra-indication
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Extracted information for LACTULOSE only.
10 g/15 ml oral solution, to be administered using a measuring device (oral syringe, measuring spoon, or cup with graduations)
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Child under 1 year: 5 ml daily (3.3 g daily) Child from 1 to 6 years: 5 to 10 ml daily (3.3 to 6.7 g daily) Child from 7 to 14 years: 10 to 15 ml daily (6.7 to 10 g daily) Child over 14 years and adult: 15 to 45 ml daily (10 to 30 g daily) Start lactulose when analgesic treatment continues more than 48 hours. Lactulose must be taken daily, until the end of the opioid treatment. Regular follow up (frequency/consistency of stools) is essential in order to adjust dosage correctly.
Source page 187
Extracted information for LACTULOSE only.
It may take up to 48 hours, or even longer, before the treatment is effective. Lactulose is not indicated in acute constipation where a rapid result is needed. If necessary, lactulose may be given in combination with a stimulant laxative (e.g. bisacodyl, senna). The oral solution may be taken undiluted, or diluted in water. The treatment should be accompanied by dietary measures (fluids and fibre).
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Below 25 °C. Do not store in a refrigerator (cristallisation).
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Filter the extracted dose blocks for this individual drug.
15 to 45 ml daily (10 to 30 g daily)
Candidate age grouping · source page 187