Therapeutic Action
Antiprotozoal, antibacterial (group of nitroimidazoles)
Source page 215
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Individual generic drug information
Extracted information for METRONIDAZOLE only.
Antiprotozoal, antibacterial (group of nitroimidazoles)
Source page 215
Amoebiasis, giardiasis, trichomoniasis Bacterial vaginitis, infections due to anaerobic bacteria (e.g. Clostridium sp, Bacteroides sp, etc.)
Source page 215
Extracted information for METRONIDAZOLE only.
Do not administer to patients with hypersensitivity to metronidazole or another nitroimidazole (tinidazole, secnidazole, etc.). May cause: gastrointestinal disturbances; rarely: allergic reactions, brownish urine, headache, dizziness. Risk of antabuse reaction when combined with alcohol. Administer with caution in patients taking oral anticoagulants (risk of haemorrhage), lithium, phenytoin, ergometrine (increased plasma concentrations of these drugs). Reduce total daily dose to one third and give once daily to patients with severe hepatic impairment. Pregnancy: no contra-indication; divide into smaller doses, avoid prolonged use. Breast-feeding: significantly excreted in milk (risk of gastrointestinal disturbances in breastfed infants); divide into smaller doses, avoid prolonged use.
Source page 216
Extracted information for METRONIDAZOLE only.
250 mg and 500 mg tablets 200 mg/5 ml oral suspension
Source page 215
Amoebiasis Child: 15 mg/kg 3 times daily Adult: 500 mg 3 times daily The treatment lasts 5 days in intestinal amoebiasis and 5 to 10 days in hepatic amoebiasis. Giardiasis Child: 30 mg/kg once daily for 3 days Adult: 2 g once daily for 3 days Trichomoniasis and bacterial vaginitis Adult: 2 g single dose In the event of trichomoniasis, also treat sexual partner. Infections due to anaerobic bacteria Child: 10 mg/kg 3 times daily Adult: 500 mg 3 times daily According to indication, metronidazole may be used in combination with other anti bacterials; treatment duration depends on indication.
Source page 215
Extracted information for METRONIDAZOLE only.
– Below 25 °C For the oral suspension: follow manufacturer’s instructions.
Source page 216
Filter the extracted dose blocks for this individual drug.
500 mg 3 times daily
Candidate age grouping · source page 215
2 g once daily for 3 days
Candidate age grouping · source page 215
2 g single dose
Candidate age grouping · source page 215
500 mg 3 times daily
Candidate age grouping · source page 215