Indications And Dose
Nervous system All forms of epilepsy except typical absence seizures ▶BY MOUTH ▶Child 1 month–11 years: Initially 1–1.5 mg/kg twice daily, then increased in steps of 2 mg/kg daily as required; maintenance 2.5–4 mg/kg 1–2 times a day ▶Child 12–17 years: 60–180 mg once daily ▶Adult: 60–180 mg once daily, dose to be taken at night Status epilepticus ▶BY INTRAVENOUS INJECTION ▶Adult: 10 mg/kg (max. per dose 1 g), dose to be administered at a rate not more than 100 mg/minute, injection to be diluted 1 in 10 with water for injections ▶BY SLOW INTRAVENOUS INJECTION ▶Neonate: Initially 20 mg/kg, dose to be administered at a rate no faster than 1 mg/kg/minute, then 2.5–5 mg/kg 1–2 times a day. ▶Child 1 month–11 years: Initially 20 mg/kg, dose to be administered at a rate no faster than 1 mg/kg/minute, then 2.5–5 mg/kg 1–2 times a day ▶Child 12–17 years: Initially 20 mg/kg (max. per dose 1 g), dose to be administered at a rate no faster than 1 mg/kg/minute, then 300 mg twice daily DOSE EQUIVALENCE AND CONVERSION ▶For therapeutic purposes phenobarbital and phenobarbital sodium may be considered equivalent in effect.
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