Indications And Dose
Treatment of acute migraine ▶BY MOUTH ▶Adult: Initially 50–100 mg for 1 dose, followed by 50–100 mg after at least 2 hours if required, to be taken only if migraine recurs (patient not responding to initial dose should not take second dose for same attack); maximum 300 mg per day ▶BY SUBCUTANEOUS INJECTION ▶Adult: Initially 6 mg for 1 dose, followed by 6 mg after at least 1 hour if required, to be taken only if migraine recurs (patient not responding to initial dose should not take second dose for same attack), dose to be administered using an auto-injector; not for intravenous injection which may cause coronary vasospasm and angina; maximum 12 mg per day ▶BY INTRANASAL ADMINISTRATION ▶Adult 18–65 years: Initially 10–20 mg, to be administered into one nostril, followed by 10–20 mg after at least 2 hours if required, to be taken only if migraine recurs (patient not responding to initial dose should not take second dose for same attack); maximum 40 mg per day Treatment of acute cluster headache ▶BY SUBCUTANEOUS INJECTION ▶Adult: Initially 6 mg for 1 dose, followed by 6 mg after at least 1 hour if required, to be taken only if headache recurs (patient not responding to initial dose should Nervous system not take second dose for same attack), dose to be administered using an auto-injector; not for intravenous injection which may cause coronary vasospasm and angina; maximum 12 mg per day ▶BY INTRANASAL ADMINISTRATION ▶Adult 18–65 years: Initially 10–20 mg, dose to be administered into one nostril, followed by 10–20 mg after at least 2 hours if required, to be taken only if headache recurs (patient not responding to initial dose should not take second dose for same attack); maximum 40 mg per day l UNLICENSED USE Not licensed for use in elderly.
Source page 525