Indications And Dose
Susceptible infections (e.g. chlamydia, rickettsia, mycoplasma) ▶BY MOUTH ▶Child 12–17 years: 250 mg 4 times a day, increased if necessary to 500 mg 3–4 times a day, increased dose used in severe infections ▶Adult: 250 mg 4 times a day, increased if necessary to 500 mg 3–4 times a day, increased dose used in severe infections Rosacea ▶BY MOUTH ▶Adult: 500 mg twice daily usually for 6–12 weeks (course may be repeated intermittently) Acne ▶BY MOUTH ▶Child 12–17 years: 500 mg twice daily for at least 3 months, if there is no improvement after the first 3 months another oral antibacterial should be used, maximum improvement usually occurs after 4 to 6 months but in more severe cases treatment may need to be continued for 2 years or longer ▶Adult: 500 mg twice daily for at least 3 months, if there is no improvement after the first 3 months another oral antibacterial should be used, maximum improvement usually occurs after 4 to 6 months but in more severe cases treatment may need to be continued for 2 years or longer Diabetic diarrhoea in autonomic neuropathy ▶BY MOUTH ▶Adult: 250 mg for 2 or 3 doses Non-gonococcal urethritis ▶BY MOUTH ▶Child 12–17 years: 500 mg 4 times a day for 7–14 days (21 days if failure or relapse after first course) ▶Adult: 500 mg 4 times a day for 7–14 days (21 days if failure or relapse after first course) Helicobacter pylori eradication [in combination with other drugs (see Helicobacter pylori infection p. 89)] ▶BY MOUTH ▶Adult: 500 mg 4 times a day for 7 days for first- and second-line eradication therapy; 10 days for third-line eradication therapy l UNLICENSED USE Not licensed for treatment of diabetic diarrhoea in autonomic neuropathy. g Tetracycline is used for the eradication of Helicobacter pylori, h but is not licensed for this indication.
Source page 622