Names and pronunciation
(al-byoo′min) AlbuKed 5%, Albuminex 5%, AlbuRx 5%, Flexbumin 5%, Albutein 5%, Plasbumin-5 Albutein 25%, Plasbumin-25
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Drug reference
(al-byoo′min) AlbuKed 5%, Albuminex 5%, AlbuRx 5%, Flexbumin 5%, Albutein 5%, Plasbumin-5 Albutein 25%, Plasbumin-25
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Func. class.: Plasma volume expander
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USES: Restores plasma volume after burns, hyperbilirubinemia, shock, hypo- proteinemia, prevention of cerebral edema, cardiopulmonary bypass proce- dures, ARDS, nephrotic syndrome
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CONTRAINDICATIONS: Hyper- sensitivity, HF, severe anemia, renal insuf- ficiency, pulmonary edema
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DOSAGE AND ROUTES Burns • Adult: IV dose to maintain plasma al- bumin at 3-4 mg/dL Hypovolemic shock • Adult: IV rapidly give 5% solution, when close to normal, infuse at ≤2-4 mL/ min (25% sol ≤1 mL/min) • Child: IV 0.5-1 g/kg/dose 5% solution, may repeat as needed, max 6 g/kg/day Nephrotic syndrome • Adult: IV 100-200 mL of 25% and loop diuretic × 7-10 days Hypoproteinemia • Adult: IV 25 g, may repeat in 15-30 min, or 50-75 g of 25% albumin infused at ≤2 mL/min • Child and infant: IV 0.5-1 g/kg/dose over 2-4 hr, may repeat q1-2days Hyperbilirubinemia/erythroblastosis fetalis • Child: IV 1 g/kg 1-2 hr before transfu- sion HIGH ALERT
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• Child: IV 0.5-1 g/kg/dose 5% solution, may repeat as needed, max 6 g/kg/day Nephrotic syndrome
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• Child and infant: IV 0.5-1 g/kg/dose over 2-4 hr, may repeat q1-2days Hyperbilirubinemia/erythroblastosis fetalis
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• Child: IV 1 g/kg 1-2 hr before transfu- sion HIGH ALERT
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