Drug reference

Alpha tocopherol

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1171

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Vitamin E deficiency because of malabsorption in congenital or hereditary chronic cholestasis ▶BY MOUTH USING ORAL SOLUTION ▶Child: 17 mg/kg daily, dose to be adjusted as necessary

PDF page 1171

Cautions

Predisposition to thrombosis

PDF page 1171

Prescribing And Dispensing Information

Tocofersolan is a water-soluble form of D-alpha tocopherol.

PDF page 1171

Safety

Interactions

→Appendix 1: vitamin E substances

PDF page 1171

Side Effects

▶Common or very common Diarrhoea ▶Uncommon Alopecia. asthenia. headache. skin reactions ▶Frequency not known Abdominal pain

PDF page 1171

Pregnancy

Manufacturer advises caution, no evidence of harm in animal studies.

PDF page 1171

Breast Feeding

Manufacturer advises use only if potential beneﬁt outweighs risk—no information available.

PDF page 1171

Hepatic Impairment

Manufacturer advises caution.

PDF page 1171

Renal Impairment

Manufacturer advises caution. Risk of renal toxicity due to polyethylene glycol content. Monitoring Manufacturer advises monitor closely in renal impairment.

PDF page 1171

Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Oral solution ▶Vedrop (Recordati Rare Diseases UK Ltd) A D-alpha tocopherol (as Tocofersolan) 50 mg per 1 ml Vedrop 50mg/ml oral solution sugar-free | 20 ml P £54.55 DT = £54.55 sugar-free | 60 ml P £163.65

PDF page 1171

Dose text by age group

Child

17 mg/kg daily, dose to be adjusted as necessary

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1171

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Alpha tocopherol

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1171

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Vitamin E deficiency because of malabsorption in congenital or hereditary chronic cholestasis ▶BY MOUTH USING ORAL SOLUTION ▶Child: 17 mg/kg daily, dose to be adjusted as necessary

PDF page 1171

Cautions

Predisposition to thrombosis

PDF page 1171

Prescribing And Dispensing Information

Tocofersolan is a water-soluble form of D-alpha tocopherol.

PDF page 1171

Safety

Interactions

→Appendix 1: vitamin E substances

PDF page 1171

Side Effects

▶Common or very common Diarrhoea ▶Uncommon Alopecia. asthenia. headache. skin reactions ▶Frequency not known Abdominal pain

PDF page 1171

Pregnancy

Manufacturer advises caution, no evidence of harm in animal studies.

PDF page 1171

Breast Feeding

Manufacturer advises use only if potential beneﬁt outweighs risk—no information available.

PDF page 1171

Hepatic Impairment

Manufacturer advises caution.

PDF page 1171

Renal Impairment

Manufacturer advises caution. Risk of renal toxicity due to polyethylene glycol content. Monitoring Manufacturer advises monitor closely in renal impairment.

PDF page 1171

Dose and formulations

Medicinal Forms

PDF page 1171

Dose text by age group

Child

17 mg/kg daily, dose to be adjusted as necessary

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1171

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.