Drug reference
Short-term use in anxiety ▶BY MOUTH ▶Adult: 250–500 micrograms 3 times a day, increased if Nervous system necessary up to 3 mg daily, for debilitated patients, use elderly dose ▶Elderly: 250 micrograms 2–3 times a day, increased if necessary up to 3 mg daily
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Respiratory depression
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Muscle weakness. organic brain changes
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NHS restrictions Alprazolam tablets are not prescribable in NHS primary care.
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→Appendix 1: alprazolam
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▶Common or very common Appetite decreased. concentration impaired. constipation. dermatitis. dry mouth. memory loss. movement disorders. sexual dysfunction. weight changes ▶Uncommon Menstruation irregular ▶Frequency not known Angioedema. autonomic dysfunction . hepatic disorders. hyperprolactinaemia. peripheral oedema. photosensitivity reaction. suicide. thinking abnormal
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Benzodiazepines are present in milk, and should be avoided if possible during breast-feeding.
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Dose adjustments Start with small doses in severe impairment.
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There can be variation in the licensing of different medicines containing the same drug. Tablet CAUTIONARY AND ADVISORY LABELS 2 ▶Xanax (Upjohn UK Ltd) Alprazolam 250 microgram Xanax 250microgram tablets | 60 tablet P £3.18 d Alprazolam 500 microgram Xanax 500microgram tablets | 60 tablet P £6.09 d eiiii F 359
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250 micrograms 2–3 times a day, increased if
First-line fragment. Read the complete Indications and Dose section above.
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