Names and pronunciation
(al-pros′ta-dil) Caverject, Caverject Impulse, Edex, Muse, Prostin VR Pediatric
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Drug reference
(al-pros′ta-dil) Caverject, Caverject Impulse, Edex, Muse, Prostin VR Pediatric
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Func. class.: Hormone
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USES: To maintain patent ductus arte- riosus (temporary treatment), erectile dysfunction
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CONTRAINDICATIONS: Hyper- sensitivity, respiratory distress syndrome, those at risk for priapism
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Black Box Warning: Apnea
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DOSAGE AND ROUTES Patent ductus arteriosus (Prostin VR Pediatric) • Infant: IV INFUSION 0.05-0.1 mcg/ kg/min until desired response, then re- duce to lowest effective amount, max 0.4 mcg/kg/min Erectile dysfunction of vasculogenic or mixed etiology, psychogenic • Men: INTRACAVERNOSAL 2.5 mcg, may increase by 2.5 mcg, may then in- crease by 5-10 mcg until adequate re- sponse occurs (max 60 mcg/dose); INTRAURETHRAL 125-250 mcg, max 2 doses/24 hr, max dose 1000 mcg; ad- minister as needed to achieve erection
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Available forms: injection 500 mcg/ mL; intracavernosal injection 10 mcg/ vial, 20 mcg/vial, 40 mcg/vial; urethral suppository 125, 250, 500, 1000 mcg HIGH ALERT
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• Infant: IV INFUSION 0.05-0.1 mcg/ kg/min until desired response, then re- duce to lowest effective amount, max 0.4 mcg/kg/min Erectile dysfunction of vasculogenic or mixed etiology, psychogenic
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• Men: INTRACAVERNOSAL 2.5 mcg, may increase by 2.5 mcg, may then in- crease by 5-10 mcg until adequate re- sponse occurs (max 60 mcg/dose); INTRAURETHRAL 125-250 mcg, max 2 doses/24 hr, max dose 1000 mcg; ad- minister as needed to achieve erection
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