Therapeutic Action
Antimalarial
PDF page 608
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Drug reference
Antimalarial
PDF page 608
Treatment of uncomplicated falciparum malaria, in combination with artesunate Treatment of uncomplicated malaria due to other Plasmodium species, in combination with artesunate, when chloroquine cannot be used Completion treatment following parenteral therapy for severe malaria, in combination with artesunate
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Do not administer in the event of previous severe adverse reaction to treatment with amodiaquine (e.g. hypersensitivity reaction, hepatitis, leucopenia, agranulocytosis). Do not administer to patients taking efavirenz. May cause: gastrointestinal disturbances, pruritus, cough, insomnia. Pregnancy: no contra-indication Breast-feeding: no contra-indication
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200 mg amodiaquine hydrochloride tablet, containing 153 mg amodiaquine base
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Child and adult: 10 mg base/kg once daily for 3 days, in combination with artesunate
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Also comes as co-packaged dispersible tablets for seasonal malaria chemoprevention in children: amodiaquine 153 mg + sulfadoxine/pyrimethamine 500 mg/25 mg and amodiaquine 76.5 mg +
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– Below 25 °C
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10 mg base/kg once daily for 3 days, in combination with artesunate
PDF page 608