Indications And Dose
Anticoagulation in patients with heparin-induced thrombocytopenia type II who require parenteral antithrombotic treatment ▶INITIALLY BY CONTINUOUS INTRAVENOUS INFUSION ▶Adult: Initially 2 micrograms/kg/minute, dose to be adjusted according to activated partial thromboplastin time, (by intravenous infusion) increased to up to 10 micrograms/kg/minute maximum duration of treatment 14 days Anticoagulation in patients with heparin-induced thrombocytopenia type II who require parenteral antithrombotic treatment (for dose in cardiac surgery, percutaneous coronary intervention, or critically ill patients) ▶BY CONTINUOUS INTRAVENOUS INFUSION ▶Adult: (consult product literature) Anticoagulation in patients with heparin-induced thrombocytopenia type II who require parenteral antithrombotic treatment (when initiating concomitant warfarin treatment) ▶BY CONTINUOUS INTRAVENOUS INFUSION ▶Adult: Reduced to 2 micrograms/kg/minute, dose should be temporarily reduced and INR measured after 4–6 hours; warfarin should be initiated at intended maintenance dose (do not give loading dose of warfarin); consult product literature for further details
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