Indications And Dose
Prevention of scurvy ▶BY MOUTH ▶Adult: 25–75 mg daily Treatment of scurvy ▶BY MOUTH ▶Adult: Not less than 250 mg daily in divided doses Blood and nutrition
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Drug reference
Prevention of scurvy ▶BY MOUTH ▶Adult: 25–75 mg daily Treatment of scurvy ▶BY MOUTH ▶Adult: Not less than 250 mg daily in divided doses Blood and nutrition
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Hyperoxaluria Hypercalcaemia. metastatic calcification
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CAUTIONS, FURTHER INFORMATION ▶Iron overload Ascorbic acid should not be given to patients with cardiac dysfunction. In patients with normal cardiac function ascorbic acid should be introduced 1 month after starting desferrioxamine.
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It is rarely necessary to prescribe more than 100 mg daily except early in the treatment of scurvy.
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→Appendix 1: ascorbic acid
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Diarrhoea. gastrointestinal disorder. hyperoxaluria. oxalate nephrolithiasis. polyuria ▶Common or very common Abdominal pain. headache. hypercalcaemia. hypercalciuria. nausea. skin reactions ▶Uncommon Appetite decreased. constipation. thirst. vomiting Overdose Symptoms of overdosage include anorexia, lassitude, nausea and vomiting, diarrhoea, constipation, weight loss, polyuria, sweating, headache, thirst, vertigo, and raised concentrations of calcium and phosphate in plasma and urine.
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High doses teratogenic in animals but therapeutic doses unlikely to be harmful.
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Caution with high doses; may cause hypercalcaemia in infant—monitor serum-calcium concentration.
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Important: all patients Blood and nutrition receiving pharmacological doses of vitamin D should have their plasma-calcium concentration checked at intervals (initially once or twice weekly) and whenever nausea or vomiting occur. eiiii F 1143
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There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: tablet, oral suspension, oral solution Tablet EXCIPIENTS: May contain Aspartame ▶Ascorbic acid (Non-proprietary) Ascorbic acid 50 mg Ascorbic acid 50mg tablets | 28 tablet G £15.08 DT = £15.08 Ascorbic acid 100 mg Ascorbic acid 100mg tablets | 28 tablet G £14.30 DT = £14.30 Ascorbic acid 200 mg Ascorbic acid 200mg tablets | 28 tablet G £19.88 DT = £19.88 Ascorbic acid 250 mg Ascorbic acid 250mg tablets | 1000 tablet P s Ascorbic acid 500 mg Ascorbic acid 500mg tablets | 28 tablet G £26.89 DT = £26.89 Chewable tablet CAUTIONARY AND ADVISORY LABELS 24 EXCIPIENTS: May contain Aspartame ▶Ascur (Ennogen Healthcare Ltd) Ascorbic acid 100 mg Ascur 100mg chewable tablets | 30 tablet £3.95 Ascorbic acid (as Sodium ascorbate) 500 mg Ascur 500mg chewable tablets sugar-free | 30 tablet £2.99 Capsule ▶BioCare (BioCare Ltd) Ascorbic acid 500 mg BioCare Vitamin C 500mg capsules | 60 capsule £7.73 | 180 capsule £19.82 Combinations available: Vitamin B substances with ascorbic acid, p. 1142. Vitamins A, C and D, p. 1140 VITAMINS AND TRACE ELEMENTS › VITAMIN D AND ANALOGUES Vitamin D and analogues f (systemic)
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25–75 mg daily
First-line fragment. Read the complete Indications and Dose section above.
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Not less than 250 mg daily in divided doses
First-line fragment. Read the complete Indications and Dose section above.
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