Drug reference
Treatment of mild to moderate Pneumocystis jirovecii (Pneumocystis carinii) pneumonia in patients intolerant of co-trimoxazole ▶BY MOUTH ▶Adult: 750 mg twice daily for 21 days, dose to be taken with food, particularly high fat food Prophylaxis against pneumocystis pneumonia ▶BY MOUTH ▶Adult: 750 mg twice daily l UNLICENSED USE Not licensed for prophylaxis against pneumocystis pneumonia.
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Elderly. initial diarrhoea and difficulty in taking with food may reduce absorption (and require alternative therapy). other causes of pulmonary disease should be sought and treated
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Flavours of oral liquid formulations may include tutti-frutti.
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→Appendix 1: antimalarials
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▶Common or very common Anaemia. angioedema. bronchospasm. diarrhoea. headache. hypersensitivity. hyponatraemia. insomnia. nausea. neutropenia. skin reactions. throat tightness. vomiting ▶Frequency not known Stevens-Johnson syndrome
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Manufacturer advises avoid unless potential benefit outweighs risk—no information available.
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Manufacturer advises avoid.
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Manufacturer advises use with caution in significant impairment and monitor closely—no information available.
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Manufacturer advises caution. Monitoring Monitor more closely in renal impairment.
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There can be variation in the licensing of different medicines containing the same drug. Oral suspension CAUTIONARY AND ADVISORY LABELS 21 ▶Atovaquone (Non-proprietary) Atovaquone 150 mg per 1 ml Atovaquone 750mg/5ml oral suspension sugar-free | 250 ml P £470.60 ▶Wellvone (GlaxoSmithKline UK Ltd) Atovaquone 150 mg per 1 ml Wellvone 750mg/5ml oral suspension sugar-free | 226 ml P £486.37 DT = £486.37
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750 mg twice daily for 21 days, dose to be taken
First-line fragment. Read the complete Indications and Dose section above.
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750 mg twice daily
First-line fragment. Read the complete Indications and Dose section above.
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