Indications And Dose
Neuromuscular blockade (short to intermediate duration) for surgery and intubation ▶INITIALLY BY INTRAVENOUS INJECTION ▶Adult: Initially 300–600 micrograms/kg, then (by intravenous injection) 100–200 micrograms/kg as required, alternatively (by intravenous injection) initially 300–600 micrograms/kg, followed by (by intravenous infusion) 300–600 micrograms/kg/hour Neuromuscular blockade during intensive care ▶INITIALLY BY INTRAVENOUS INJECTION ▶Adult: Initially 300–600 micrograms/kg, initial dose is optional, then (by intravenous infusion) 270–1770 micrograms/kg/hour; (by intravenous infusion) usual dose 650–780 micrograms/kg/hour DOSES AT EXTREMES OF BODY-WEIGHT ▶To avoid excessive dosage in obese patients, dose should be calculated on the basis of ideal body-weight.
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