Drug Action
Bambuterol is a pro-drug of terbutaline.
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Drug reference
Bambuterol is a pro-drug of terbutaline.
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Asthma (patients who have previously tolerated beta2- agonists) | Other conditions associated with reversible airways obstruction (patients who have previously tolerated beta2-agonists) ▶BY MOUTH ▶Adult: 20 mg once daily, dose to be taken at bedtime Asthma (patients who have not previously tolerated beta2-agonists) | Other conditions associated with reversible airways obstruction (patients who have not previously tolerated beta2-agonists) ▶BY MOUTH ▶Adult: Initially 10 mg once daily for 1–2 weeks, then increased if necessary to 20 mg once daily, dose to be taken at bedtime
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→Appendix 1: beta2 agonists
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▶Common or very common Anxiety. behaviour abnormal. muscle cramps. sleep disorder ▶Frequency not known Akathisia. angioedema. bronchospasm. circulatory collapse. hypersensitivity. hypotension. skin reactions
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Manufacturer advises avoid—no information available.
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Manufacturer advises avoid—no information available.
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Manufacturer advises avoid in severe impairment or cirrhosis (risk of unpredictable conversion to terbutaline; direct terbutaline use preferred).
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Dose adjustments Reduce initial dose by half if eGFR less than 50 mL/minute/1.73 m2.
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There can be variation in the licensing of different medicines containing the same drug. Tablet ▶Bambec (AstraZeneca UK Ltd) Bambuterol hydrochloride 10 mg Bambec 10mg tablets | 30 tablet P £30.99 DT = £30.99 eiiii F above
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20 mg once daily, dose to be taken at bedtime
First-line fragment. Read the complete Indications and Dose section above.
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Initially 10 mg once daily for 1–2 weeks, then
First-line fragment. Read the complete Indications and Dose section above.
PDF page 286