Names and pronunciation
(bay-ta-meth′a-sone) Betaderm , Betagel , Betaprolene Cream , Betaflam , Betesol , Celestoderm V , Diprolene, Diprolene AF, Sernivo Luxiq
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Drug reference
(bay-ta-meth′a-sone) Betaderm , Betagel , Betaprolene Cream , Betaflam , Betesol , Celestoderm V , Diprolene, Diprolene AF, Sernivo Luxiq
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Func. class.: Corticosteroid, topical
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ACTION: Crosses cell membrane to attach to receptors to decrease inflam- mation, itching; inhibits multiple inflam- matory cytokines
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USES: Inflammation/itching cortico- steroid-responsive dermatoses on the skin/scalp
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CONTRAINDICATIONS: Hyper- sensitivity, use of some preparations on face, axilla, groin Precautions: Pregnancy, skin infections
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SIDE EFFECTS INTEG: Burning, folliculitis, pruritus, dermatitis, maceration, erythema MISC: Hyperglycemia, glycosuria, Cush- ing’s syndrome, HPA axis suppression
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DOSAGE AND ROUTES • Adult: TOP 1-2 times/day (dipropio- nate) or 1-3 times/day (valerate); or ap- ply spray 0.05% bid up to 4 wk (plaque psoriasis, mild to moderate)
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Available forms: dipropionate: gel, lotion, ointment, cream, spray 0.05%; valerate: cream, lotion, ointment 0.1%, foam 0.12%
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Assess: • Skin reactions: burning, pruritus, fol- liculitis, dermatitis • HPA axis suppression: usually rare with topical products
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Evaluate: • Decreased itching; inflammation on the skin, scalp
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CLINICAL CONSIDERATIONS
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Patient and caregiver information: Topical route: • That betamethasone valerate may be used with occlusive dressings for psoria- sis or recalcitrant conditions; not to use dipropionate with occlusive dressings • Avoid use of topical corticosteroids on face Cream/ointment/lotion: • To apply sparingly in a thin film, using gloves, and to rub gently into the cleansed, slightly moist affected area • Not to use on broken, wet skin; area of infection; face or groin; axilla Gel: • To apply sparingly in a thin film, using gloves, and to rub gently into the cleansed, slightly moist affected area Scalp foam: • Gently massage into affected area until foam disappears; repeat until entire af- fected scalp area is treated • That treatment should be limited to 2 wk HIGH ALERT
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PHARMACOKINETICS Unknown
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• Adult: TOP 1-2 times/day (dipropio- nate) or 1-3 times/day (valerate); or ap- ply spray 0.05% bid up to 4 wk (plaque psoriasis, mild to moderate)
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