Drug reference
Helicobacter pylori eradication [in combination with other drugs (see Helicobacter pylori infection p. 89)] ▶BY MOUTH ▶Adult: 525 mg 4 times a day for 7 days for first- and second-line eradication therapy; 10 days for third-line eradication therapy l UNLICENSED USE g Bismuth subsalicylate is used for the eradication of Helicobacter pylori, h but is not licensed for this indication.
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Children under 16 years (risk of Reye’s syndrome)
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Blood clotting disorders. gout
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Contra-indicated in patients with a history of hypersensitivity to aspirin or other salicylates.
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→Appendix 1: bismuth
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▶Common or very common Black faeces. black tongue Overdose The main features of salicylate poisoning are hyperventilation, tinnitus, deafness, vasodilatation, and sweating. Bismuth overdose may present as acute encephalopathy with confusion, myoclonus, tremor, dysarthria and gait disturbances. Gastrointestinal disturbances, skin reactions, discolouration of mucous membranes and renal impairment may also be present.
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Manufacturer advises avoid unless essential—no information available.
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Manufacturer advises avoid unless essential—no information available.
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There can be variation in the licensing of different medicines containing the same drug. Oral suspension Gastro-intestinal system CAUTIONARY AND ADVISORY LABELS 12 ▶Pepto-Bismol (Procter & Gamble (Health & Beauty Care) Ltd) Bismuth subsalicylate 17.5 mg per 1 ml Pepto-Bismol 17.5mg/1ml oral suspension sugar-free | 120 ml p s Chewable tablet CAUTIONARY AND ADVISORY LABELS 12, 24 ▶Pepto-Bismol (Procter & Gamble (Health & Beauty Care) Ltd) Bismuth subsalicylate 262.5 mg Pepto-Bismol 262.5mg chewable tablets sugar-free | 12 tablet p s GASTROPROTECTIVE COMPLEXES AND CHELATORS Chelates and complexes Overview Sucralfate below may act by protecting the mucosa from acid-pepsin attack in gastric and duodenal ulcers. It is a complex of aluminium hydroxide and sulfated sucrose but has minimal antacid properties.
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525 mg 4 times a day for 7 days for first- and
First-line fragment. Read the complete Indications and Dose section above.
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