Drug reference

Budesonide

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 295, 296

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Drug Action

Budesonide is a glucocorticoid, which exerts signiﬁcant local anti-inﬂammatory effects.

PDF page 295

Indications And Dose

Prophylaxis of mild to moderate asthma (in patients stabilised on twice daily dose) ▶BY INHALATION OF POWDER ▶Child 6–11 years: 200–400 micrograms once daily, dose to be given in the evening ▶Child 12–17 years: 200–400 micrograms once daily (max. per dose 800 micrograms), dose to be given in the evening ▶Adult: 200–400 micrograms once daily (max. per dose 800 micrograms), dose to be given in the evening Prophylaxis of asthma ▶BY INHALATION OF POWDER ▶Child 6–11 years: 100–400 micrograms twice daily, dose continued → to be adjusted as necessary ▶Child 12–17 years: 100–800 micrograms twice daily, dose to be adjusted as necessary ▶Adult: 100–800 micrograms twice daily, dose to be adjusted as necessary ▶BY INHALATION OF NEBULISED SUSPENSION ▶Child 6 months–11 years: 125–500 micrograms twice Respiratory system daily, adjusted according to response; maximum 2 mg per day ▶Child 12–17 years: Initially 0.25–1 mg twice daily, adjusted according to response, doses higher than recommended max. may be used in severe disease; maximum 2 mg per day ▶Adult: Initially 0.25–1 mg twice daily, adjusted according to response, doses higher than recommended max. may be used in severe disease; maximum 2 mg per day POTENCY ▶Dose adjustments may be required for some inhaler devices, see under individual preparations. BUDELIN NOVOLIZER ® Prophylaxis of asthma ▶BY INHALATION OF POWDER ▶Adult: 200–800 micrograms twice daily, dose is adjusted as necessary Alternative in mild to moderate asthma, for patients previously stabilised on a twice daily dose ▶BY INHALATION OF POWDER ▶Adult: 200–400 micrograms once daily (max. per dose 800 micrograms), to be taken in the evening PULMICORT ® RESPULES Prophylaxis of asthma ▶BY INHALATION OF NEBULISED SUSPENSION ▶Child 3 months–11 years: Initially 0.5–1 mg twice daily, reduced to 250–500 micrograms twice daily ▶Child 12–17 years: Initially 1–2 mg twice daily, reduced to 0.5–1 mg twice daily ▶Adult: Initially 1–2 mg twice daily, reduced to 0.5–1 mg twice daily PULMICORT ® TURBOHALER Prophylaxis of asthma ▶BY INHALATION OF POWDER ▶Adult: 100–800 micrograms twice daily, dose to be adjusted as necessary Alternative in mild to moderate asthma, for patients previously stabilised on a twice daily dose ▶BY INHALATION OF POWDER ▶Adult: 200–400 micrograms once daily (max. per dose 800 micrograms), to be taken in the evening

PDF pages 295, 296

Safety

Interactions

→Appendix 1: corticosteroids

PDF page 296

Dose and formulations

Directions For Administration

Budesonide nebuliser suspension is not suitable for use in ultrasonic nebulisers.

PDF page 296

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Inhalation powder CAUTIONARY AND ADVISORY LABELS 8, 10 ▶Budelin Novolizer (Mylan) Budesonide 200 microgram per 1 dose Budelin Novolizer 200micrograms/dose inhalation powder | 100 dose P £14.86 DT = £14.86 Budelin Novolizer 200micrograms/dose inhalation powder refill | 100 dose P £9.59 DT = £9.59 ▶Easyhaler (budesonide) (Orion Pharma (UK) Ltd) Budesonide 100 microgram per 1 dose Easyhaler Budesonide 100micrograms/dose dry powder inhaler | 200 dose P £8.86 DT = £14.25 Budesonide 200 microgram per 1 dose Easyhaler Budesonide 200micrograms/dose dry powder inhaler | 200 dose P £17.71 Budesonide 400 microgram per 1 dose Easyhaler Budesonide 400micrograms/dose dry powder inhaler | 100 dose P £17.71 ▶Pulmicort Turbohaler (AstraZeneca UK Ltd) Budesonide 100 microgram per 1 dose Pulmicort 100 Turbohaler | 200 dose P £14.25 DT = £14.25 Budesonide 200 microgram per 1 dose Pulmicort 200 Turbohaler | 100 dose P £14.25 DT = £14.25 Budesonide 400 microgram per 1 dose Pulmicort 400 Turbohaler | 50 dose P £14.25 DT = £14.25 Nebuliser liquid CAUTIONARY AND ADVISORY LABELS 8, 10 ▶Budesonide (Non-proprietary) Budesonide 250 microgram per 1 ml Budesonide 500micrograms/2ml nebuliser liquid unit dose vials | 20 unit dose P £26.03 DT = £25.94 Budesonide 500 microgram per 1 ml Budesonide 1mg/2ml nebuliser liquid unit dose vials | 20 unit dose P £39.47 DT = £39.47 ▶Pulmicort Respules (AstraZeneca UK Ltd) Budesonide 250 microgram per 1 ml Pulmicort 0.5mg Respules | 20 unit dose P £31.70 DT = £25.94 Budesonide 500 microgram per 1 ml Pulmicort 1mg Respules | 20 unit dose P £48.00 DT = £39.47

PDF page 296

Clinical care

Patient And Carer Advice

With high doses, a steroid card should be supplied. Patients or carers should be given advice on how to administer budesonide dry powder inhaler and nebuliser suspension. Medicines for Children leaflet: Budesonide inhaler for asthma prevention (prophylaxis) www.medicinesforchildren.org.uk/ budesonide-inhaler-asthma-prevention-prophylaxis BUDELIN NOVOLIZER ® Patients or carers should be given advice on administration of Budelin Novolizer ®.

PDF page 296

Dose text by age group

Child 6–11 years

200–400 micrograms once daily, dose

First-line fragment. Read the complete Indications and Dose section above.

PDF page 295

Child 12–17 years

200–400 micrograms once daily (max.

First-line fragment. Read the complete Indications and Dose section above.

PDF page 295

Child 6–11 years

100–400 micrograms twice daily, dose

First-line fragment. Read the complete Indications and Dose section above.

PDF page 295

Child 12–17 years

100–800 micrograms twice daily, dose

First-line fragment. Read the complete Indications and Dose section above.

PDF page 296

Child 6 months–11 years

125–500 micrograms twice

First-line fragment. Read the complete Indications and Dose section above.

PDF page 296

Child 12–17 years

Initially 0.25–1 mg twice daily,

First-line fragment. Read the complete Indications and Dose section above.

PDF page 296

Child 3 months–11 years

Initially 0.5–1 mg twice daily,

First-line fragment. Read the complete Indications and Dose section above.

PDF page 296

Child 12–17 years

Initially 1–2 mg twice daily, reduced

First-line fragment. Read the complete Indications and Dose section above.

PDF page 296

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Budesonide

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 295, 296

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Drug Action

Budesonide is a glucocorticoid, which exerts signiﬁcant local anti-inﬂammatory effects.

PDF page 295

Indications And Dose

PDF pages 295, 296

Safety

Interactions

→Appendix 1: corticosteroids

PDF page 296

Dose and formulations

Directions For Administration

Budesonide nebuliser suspension is not suitable for use in ultrasonic nebulisers.

PDF page 296

Medicinal Forms

PDF page 296

Clinical care

Patient And Carer Advice

PDF page 296

Dose text by age group

Child 6–11 years

200–400 micrograms once daily, dose

First-line fragment. Read the complete Indications and Dose section above.

PDF page 295

Child 12–17 years

200–400 micrograms once daily (max.

First-line fragment. Read the complete Indications and Dose section above.

PDF page 295

Child 6–11 years

100–400 micrograms twice daily, dose

First-line fragment. Read the complete Indications and Dose section above.

PDF page 295

Child 12–17 years

100–800 micrograms twice daily, dose

First-line fragment. Read the complete Indications and Dose section above.

PDF page 296

Child 6 months–11 years

125–500 micrograms twice

First-line fragment. Read the complete Indications and Dose section above.

PDF page 296

Child 12–17 years

Initially 0.25–1 mg twice daily,

First-line fragment. Read the complete Indications and Dose section above.

PDF page 296

Child 3 months–11 years

Initially 0.5–1 mg twice daily,

First-line fragment. Read the complete Indications and Dose section above.

PDF page 296

Child 12–17 years

Initially 1–2 mg twice daily, reduced

First-line fragment. Read the complete Indications and Dose section above.

PDF page 296

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.