Drug reference
Oedema ▶BY MOUTH ▶Adult: 1 mg, dose to be taken in the morning, then 1 mg after 6–8 hours if required ▶Elderly: 500 micrograms daily, this lower dose may be sufficient in elderly patients Oedema, severe cases ▶BY MOUTH ▶Adult: Initially 5 mg daily, increased in steps of 5 mg every 12–24 hours, adjusted according to response
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→Appendix 1: loop diuretics
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▶Common or very common Dehydration. hypotension. skin reactions ▶Uncommon Breast pain. chest discomfort. ear pain. vertigo ▶Rare or very rare Hearing impairment ▶Frequency not known Arthralgia. encephalopathy. gastrointestinal discomfort. gynaecomastia. hyperglycaemia. hyperuricaemia. muscle cramps. musculoskeletal pain (with high doses in renal failure)
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Bumetanide should not be used to treat gestational hypertension because of the maternal hypovolaemia associated with this condition.
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No information available. May inhibit lactation.
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There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: oral suspension Oral solution ▶Bumetanide (Non-proprietary) Bumetanide 200 microgram per 1 ml Bumetanide 1mg/5ml oral solution sugar-free | 150 ml P £198.00 DT = £198.00 Tablet ▶Bumetanide (Non-proprietary) Bumetanide 1 mg Bumetanide 1mg tablets | 28 tablet P £7.35 DT = £2.45 Bumetanide 5 mg Bumetanide 5mg tablets | 28 tablet P £9.81 DT = £9.76 Combinations available: Amiloride with bumetanide, p. 244
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500 micrograms daily, this lower dose may be
First-line fragment. Read the complete Indications and Dose section above.
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