Drug reference

Bupivacaine with fentanyl

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1434

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Anaesthesia During labour (once epidural block established) ▶BY CONTINUOUS LUMBAR EPIDURAL INFUSION ▶Adult: 10–18.75 mg/hour, dose of bupivacaine to be administered, maximum 400 mg bupivacaine in 24 hours and 16–30 micrograms/hour, dose of fentanyl to be administered, maximum 720 micrograms fentanyl in 24 hours Postoperative pain (once epidural block established) ▶BY CONTINUOUS EPIDURAL INFUSION ▶Adult: 4–18.75 mg/hour, dose of bupivacaine to be administered, maximum 400 mg bupivacaine in 24 hours and 8–30 micrograms/hour, dose of fentanyl to be administered, maximum 720 micrograms fentanyl in 24 hours, to be administered by thoracic, upper abdominal or lower abdominal epidural infusion

PDF page 1434

Safety

Interactions

→Appendix 1: anaesthetics, local. opioids

PDF page 1434

Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: infusion, solution for infusion Solution for infusion ▶Bufyl (Advanz Pharma) Fentanyl 2 microgram per 1 ml, Bupivacaine hydrochloride 1 mg per 1 ml Bufyl 1mg/ml and 2micrograms/ml 500ml infusion bags | 5 bag P £46.00 (Hospital only) b Bufyl 1mg/ml and 2micrograms/ml 250ml infusion bags | 5 bag P £42.50 (Hospital only) b Fentanyl (as Fentanyl citrate) 2 microgram per 1 ml, Bupivacaine hydrochloride 1.25 mg per 1 ml Bufyl 1.25mg/ml and 2micrograms/ml 250ml infusion bags | 5 bag P £45.25 (Hospital only) b Bufyl 1.25mg/ml and 2micrograms/ml 500ml infusion bags | 10 bag P £92.00 (Hospital only) b ANALGESICS › NON-STEROIDAL ANTI- INFLAMMATORY DRUGS

PDF page 1434

Dose text by age group

Adult

10–18.75 mg/hour, dose of bupivacaine to be

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1434

Adult

4–18.75 mg/hour, dose of bupivacaine to be

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1434

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Bupivacaine with fentanyl

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1434

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

PDF page 1434

Safety

Interactions

→Appendix 1: anaesthetics, local. opioids

PDF page 1434

Dose and formulations

Medicinal Forms

PDF page 1434

Dose text by age group

Adult

10–18.75 mg/hour, dose of bupivacaine to be

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1434

Adult

4–18.75 mg/hour, dose of bupivacaine to be

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1434

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.