Drug reference
Prevention of uterine atony after caesarean section ▶BY SLOW INTRAVENOUS INJECTION ▶Adult: 100 micrograms for 1 dose, to be given over 1 minute, administer as soon as possible after delivery, preferably before removal of placenta
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Eclampsia. epilepsy. pre-eclampsia
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Asthma. cardiovascular disease (avoid if severe). hyponatraemia. migraine
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Scottish Medicines Consortium (SMC) decisions The Scottish Medicines Consortium has advised (January 2018) that carbetocin (Pabal ®) is not recommended for use within NHS Scotland for the prevention of uterine atony following delivery of the infant by Caesarean section under epidural or spinal anaesthesia as the economic case was not demonstrated.
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▶Common or very common Chest pain. chills. dizziness. dyspnoea. feeling hot. flushing. headache. hypotension. nausea. pain. pruritus. taste metallic. tremor. vomiting ▶Frequency not known Hyperhidrosis. tachycardia
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Manufacturer advises avoid in hepatic disease.
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Manufacturer advises avoid.
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There can be variation in the licensing of different medicines containing the same drug. Solution for injection ▶Pabal (Ferring Pharmaceuticals Ltd) Carbetocin 100 microgram per 1 ml Pabal 100micrograms/1ml solution for injection vials | 5 vial P £88.20 (Hospital only) PROSTAGLANDINS AND ANALOGUES
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100 micrograms for 1 dose, to be given over
First-line fragment. Read the complete Indications and Dose section above.
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