Indications And Dose
Hypertension ▶BY MOUTH ▶Adult: Initially 12.5 mg once daily for 2 days, then increased to 25 mg once daily; increased if necessary up to 50 mg daily, dose to be increased at intervals of at least 2 weeks and can be given as a single dose or in divided doses ▶Elderly: Initially 12.5 mg daily, initial dose may provide satisfactory control Angina ▶BY MOUTH ▶Adult: Initially 12.5 mg twice daily for 2 days, then increased to 25 mg twice daily Adjunct to diuretics, digoxin, or ACE inhibitors in symptomatic chronic heart failure ▶BY MOUTH ▶Adult: Initially 3.125 mg twice daily, dose to be taken with food, then increased to 6.25 mg twice daily, then increased to 12.5 mg twice daily, then increased to 25 mg twice daily, dose should be increased at intervals of at least 2 weeks up to the highest tolerated dose, max. 25 mg twice daily in patients with severe heart failure or body-weight less than 85 kg; max. 50 mg twice daily in patients over 85 kg
PDF page 182