Therapeutic Action
First-generation cephalosporin antibacterial
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Drug reference
First-generation cephalosporin antibacterial
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Skin infections due to staphylococci and/or streptococci: impetigo, furuncle, erysipelas and superficial cellulitis
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Do not administer to patients with allergy to cephalosporin. Administer with caution to patients with allergy to penicillin (cross-sensitivity may occur) and severe renal impairment (reduce the dose). May cause: gastrointestinal disturbances (particularly diarrhoea), allergic reactions (skin eruption, fever, pruritus). Pregnancy: no contra-indication Breast-feeding: no contra-indication
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250 mg capsule 125 mg/5 ml powder for oral suspension,: to be reconstituted with filtered water to be administered using a measuring device (oral syringe, measuring spoon, or cup with graduations)
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Neonate under 7 days: 25 mg/kg 2 times daily Neonate 7 to 28 days: 25 mg/kg 3 times daily The exact dose should be calculated according to the newborn’s weight. Child 1 month to under 12 years: 12.5 to 25 mg/kg 2 times daily Child 12 years and over and adult: 1 g 2 times daily 125 mg/5 ml 250 mg Age Weight Daily dose oral susp. capsule 1 to < 5 months 4 to < 7 kg 125 mg x 2 5 ml x 2 − 5 months to < 3 years 7 to < 15 kg 187.5 mg x 2 7.5 ml x 2 − 3 to < 6 years 15 to < 20 kg 250 mg x 2 10 ml x 2 – 6 to < 12 years 20 to < 40 kg 500 mg x 2 – 2 cap x 2 ≥ 12 years and adult ≥ 40 kg 1 g x 2 – 4 cap x 2
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Impetigo, furuncle: 7 days Erysipelas, cellulitis: 7 to 10 days
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Take preferably between meals.
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– – Below 25 °C For the oral suspension (powder or reconstituted suspension): follow manufacturer’s instructions.
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1 g 2 times daily
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