Names and pronunciation
(sef-tar′oh-leen) Teflaro
PDF page 247
Loading InternPractice…
Drug reference
(sef-tar′oh-leen) Teflaro
PDF page 247
Func. class.: Antiinfective-cephalosporin C derivative (fifth generation)
PDF page 247
USES: Acute bacterial skin/skin struc- ture infections (ABSSI), bacterial com- munity-acquired pneumonia
PDF page 247
CONTRAINDICATIONS: Cepha- losporin hypersensitivity Precautions: Child/infant/neonate, breast- feeding, elderly patients, antimicrobial resistance, carbapenem/penicillin hyper- sensitivity, coagulopathy, colitis, dialysis, diarrhea, GI disease, hypoprothrombin- emia, IBS, pregnancy, pseudomembranous colitis, renal disease, ulcerative colitis, viral infection, vitamin K deficiency
PDF page 247
DOSAGE AND ROUTES • Adult: IV 600 mg q12hr × 5-14 days (skin/skin-structure infections) or × 5-7 days (bacterial community-acquired pneu- monia) • Child 2-17 yr and >33 kg: IV 400 mg q8hr or 600 mg q12hr; 2-17 yr and <33 kg; 12 mg/kg q8hr • Child 2 mo to <2 yr: IV 8 mg/kg q8hr Renal dose • Adult: IV CCr >30-≤50 mL/min, 400 mg q12hr; CCr ≥15-≤30 mL/min, 300 mg q12hr; CCr <15 mL/min, 200 mg q12hr, includes hemodialysis HIGH ALERT
PDF page 247
• Adult: IV 600 mg q12hr × 5-14 days (skin/skin-structure infections) or × 5-7 days (bacterial community-acquired pneu- monia)
PDF page 247
• Adult: IV CCr >30-≤50 mL/min, 400 mg q12hr; CCr ≥15-≤30 mL/min, 300 mg q12hr; CCr <15 mL/min, 200 mg q12hr, includes hemodialysis HIGH ALERT
PDF page 247