Names and pronunciation
(set-roe-ree′lix) Cetrotide
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Drug reference
(set-roe-ree′lix) Cetrotide
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Func. class.: Gonadotropin-releasing hormone antagonist
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Chem. class.: Synthetic decapeptide
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USES: For inhibition of premature LH surges in women undergoing controlled ovarian hyperstimulation
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CONTRAINDICATIONS: Preg- nancy, breastfeeding, hypersensitivity, latex allergy, renal disease, KRA5 mutation
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DOSAGE AND ROUTES Single-dose regimen • Adult: SUBCUT 3 mg when serum es- tradiol level at appropriate stimulation response, usually on stimulation day 7; if hCG not given within 4 days after injec- tion of 3 mg cetrorelix, give 0.25 mg daily until day of hCG administration Multiple-dose regimen • Adult: SUBCUT 0.25 mg given on stimulation day 5 (either morning or evening) or 6 (morning) and continued daily until day hCG is given
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Available forms: Powder for injection 0.25 mg HIGH ALERT
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• Adult: SUBCUT 3 mg when serum es- tradiol level at appropriate stimulation response, usually on stimulation day 7; if hCG not given within 4 days after injec- tion of 3 mg cetrorelix, give 0.25 mg daily until day of hCG administration Multiple-dose regimen
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• Adult: SUBCUT 0.25 mg given on stimulation day 5 (either morning or evening) or 6 (morning) and continued daily until day hCG is given
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