Indications And Dose
Reduction of absorption of poisons in the gastro-intestinal system ▶BY MOUTH ▶Neonate: 1 g/kg. ▶Child 1 month–11 years: 1 g/kg (max. per dose 50 g) ▶Child 12–17 years: 50 g ▶Adult: 50 g Active elimination of poisons ▶BY MOUTH ▶Neonate: 1 g/kg every 4 hours, dose may be reduced and the frequency increased if not tolerated, reduced dose Emergency treatment of poisoning may compromise efficacy. ▶Child 1 month–11 years: 1 g/kg every 4 hours (max. per dose 50 g), dose may be reduced and the frequency increased if not tolerated, reduced dose may compromise efficacy ▶Child 12–17 years: Initially 50 g, then 50 g every 4 hours, reduced if not tolerated to 25 g every 2 hours, alternatively 12.5 g every 1 hour, reduced dose may compromise efficacy ▶Adult: Initially 50 g, then 50 g every 4 hours, reduced if not tolerated to 25 g every 2 hours, alternatively 12.5 g every 1 hour, reduced dose may compromise efficacy Accelerated elimination of teriflunomide ▶BY MOUTH USING GRANULES ▶Adult: 50 g every 12 hours for 11 days Accelerated elimination of leflunomide (washout procedure) ▶BY MOUTH USING GRANULES ▶Adult: 50 g 4 times a day for 11 days l UNLICENSED USE ▶In adults Activated charcoal doses in BNF may differ from those in product literature.
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