Indications And Dose
Cerebrotendinous xanthomatosis (specialist use only) ▶BY MOUTH ▶Adult: Initially 750 mg daily in 3 divided doses, increased if necessary up to 1000 mg daily in divided doses
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Drug reference
Cerebrotendinous xanthomatosis (specialist use only) ▶BY MOUTH ▶Adult: Initially 750 mg daily in 3 divided doses, increased if necessary up to 1000 mg daily in divided doses
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Non-functioning gall bladder. radio-opaque stones
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→Appendix 1: chenodeoxycholic acid
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Constipation
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Manufacturer advises avoid—fetotoxicity reported in animal studies.
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Manufacturer advises monitor—no information available.
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Manufacturer advises monitor—no information available.
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Manufacturer advises to monitor serum cholestanol levels and/or urine bile alcohols every 3 months during the initiation of therapy and dose adjustment, and then at least annually; liver function should also be monitored during initiation of therapy and then at least annually; additional or more frequent investigations may need to be undertaken to monitor therapy during periods of fast growth or concomitant disease.
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For administration by mouth in patients who are unable to swallow capsules and/or need to take a dose below 250 mg, manufacturer advises to add capsule contents to sodium bicarbonate solution 8.4%—for further information, consult product literature. Gastro-intestinal system
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There can be variation in the licensing of different medicines containing the same drug. Capsule A ▶Chenodeoxycholic acid (non-proprietary) Chenodeoxycholic acid 250 mg Chenodeoxycholic acid 250mg capsules | 100 capsule P £14,000.00 DT = £9,999.99
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Initially 750 mg daily in 3 divided doses,
First-line fragment. Read the complete Indications and Dose section above.
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