Therapeutic Action
Macrolide antibacterial
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Drug reference
Macrolide antibacterial
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Eradication of Helicobacter pylori, in combination with omeprazole and amoxicillin
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Do not administer to patients with allergy to clarithromycin or another macrolide. May cause: headache, taste disturbances, insomnia, gastrointestinal disturbances, reversible hearing disorders; heart rhythm disorders (QT prolongation); hypersensitivity reactions sometimes severe (in this event, stop treatment immediately). Administer with caution and reduce dosage by half in patients with severe renal impairment. Avoid combination with drugs that prolong the QT interval: amiodarone, antimalarials, antipsychotics, efavirenz, fluconazole, fluoroquinolones, hydroxyzine, ondansetron, etc. Administer with caution and monitor combination with: oral antidiabetics, atorvastatin, carbamazepine, daclatasvir, digoxin, phenytoin, rifabutin (increased plasma concentrations of these drugs). Pregnancy: avoid (safety not established) Breast-feeding: no contra-indication
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500 mg tablet
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Adult: 500 mg 2 times daily for 7 days
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Clarithromycin is also used for the treatment of non-tuberculous mycobacterial infections.
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Below 25 °C
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500 mg 2 times daily for 7 days
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