Therapeutic Action
Lincosamide antibacterial
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Drug reference
Lincosamide antibacterial
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Severe staphylococcal and/or streptococcal infections (e.g. erysipelas, cellulitis, pneumonia): in betalactam-allergic patients in infections due to methicillin-resistant Staphylococcus aureus Uncomplicated cutaneous anthrax Completion treatment following therapy with parenteral clindamycin
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Do not administer to patients with allergy to lincosamides or history of pseudomembranous colitis. Reduce dosage in patients with hepatic impairment. May cause: pseudomembranous colitis, rash, jaundice, severe allergic reactions. In these cases, stop treatment. In the event of pseudomembranous colitis, treat for Clostridium difficile infection (oral metronidazole). Pregnancy: no contra-indication Breast-feeding: use only when there is no therapeutic alternative. Check infant’s stools (risk of pseudomembranous colitis).
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150 mg and 300 mg capsules
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Child: 10 to 13 mg/kg (max. 600 mg) 3 times daily Adult: 600 mg 3 times daily Age Weight 150 mg capsule 300 mg capsule 1 to < 6 years 10 to < 20 kg 1 cap x 3 – 6 to < 9 years 20 to < 30 kg – 1 cap x 3 9 to < 13 years 30 to < 45 kg 3 cap x 3 – ≥ 13 years and adult ≥ 45 kg – 2 cap x 3
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Erysipelas, cellulitis: 7 to 10 days Cutaneous anthrax: 7 to 14 days depending on severity Pneumonia: 10 to 14 days
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Take capsules with a full glass of water (risk of esophageal irritation). If needed, open the capsule and mix the content into a spoon with food or fruit juice to mask the unpleasant taste. Clindamycin is use in combination with quinine for the treatment of malaria in pregnant women (10 mg/kg 2 times daily for 7 days).
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– – Below 25 °C
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10 to 13 mg/kg (max. 600 mg) 3 times daily
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600 mg 3 times daily
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