Drug reference
Constipation in palliative care ▶BY MOUTH USING ORAL SUSPENSION ▶Child 6–11 years: 5 mL once daily, to be taken at night ▶Child 12–17 years: 5–15 mL once daily, to be taken at night ▶Adult: 5–15 mL once daily, to be taken at night DOSE EQUIVALENCE AND CONVERSION ▶Co-danthrusate suspension contains dantron 50 mg and docusate sodium 60 mg per 5 mL.
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Acute abdominal conditions. acute inflammatory bowel disease. intestinal obstruction. severe dehydration
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Excessive use of stimulant laxatives can cause diarrhoea and related effects such as hypokalaemia. may cause local irritation. rodent studies indicate potential carcinogenic risk CAUTIONS, FURTHER INFORMATION ▶Local irritation Avoid prolonged contact with skin (incontinent patients—risk of irritation and excoriation).
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→Appendix 1: docusate sodium
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Gastrointestinal disorders. skin reactions. urine orange
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Manufacturers advise avoid—limited information available.
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Manufacturers advise avoid—no information available.
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There can be variation in the licensing of different medicines containing the same drug. Oral suspension CAUTIONARY AND ADVISORY LABELS 14 (urine orange) ▶Co-danthrusate (Non-proprietary) Dantron 10 mg per 1 ml, Docusate sodium 12 mg per 1 ml Co- danthrusate 50mg/60mg/5ml oral suspension sugar free sugar-free | 200 ml P £202.50 DT = £202.50
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5 mL once daily, to be taken at night
First-line fragment. Read the complete Indications and Dose section above.
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5–15 mL once daily, to be taken at
First-line fragment. Read the complete Indications and Dose section above.
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5–15 mL once daily, to be taken at night
First-line fragment. Read the complete Indications and Dose section above.
PDF page 88
