Names and pronunciation
(koe-bi-me′ti-nib) C Cotellic
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Drug reference
(koe-bi-me′ti-nib) C Cotellic
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Func. class.: Antineoplastic
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USES: Orphan drug. For the treatment of unresectable or metastatic melanoma in patients with a BRAF V600E or V600K muta- tion, in combination with vemurafenib
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CONTRAINDICATIONS: Hyper- sensitivity
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DOSAGE AND ROUTES • Adult: PO 60 mg (three 20-mg tablets) daily × 21 days, in combination with vemu- rafenib 960 mg bid × 28 days; repeat cycle q28days until disease progression or unacceptable toxicity
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Available forms: Tablets 20 mg HIGH ALERT
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• Adult: PO 60 mg (three 20-mg tablets) daily × 21 days, in combination with vemu- rafenib 960 mg bid × 28 days; repeat cycle q28days until disease progression or unacceptable toxicity
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