Drug Action
Dequalinium chloride is a bactericidal anti- infective which causes bacterial cell death by increasing cell permeability and reducing enzyme activity.
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Drug reference
Dequalinium chloride is a bactericidal anti- infective which causes bacterial cell death by increasing cell permeability and reducing enzyme activity.
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Bacterial vaginosis ▶BY VAGINA ▶Adult 18–55 years: 10 mg once daily for 6 days, inserted at night
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Vaginal ulceration
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Scottish Medicines Consortium (SMC) decisions The Scottish Medicines Consortium has advised (November 2016) that dequalinium chloride (Fluomizin ®) is accepted for restricted use within NHS Scotland for treatment of bacterial vaginosis in patients for whom the initial treatment is not effective or well tolerated. All Wales Medicines Strategy Group (AWMSG) decisions The All Wales Medicines Strategy Group has advised (November 2016) that dequalinium chloride (Fluomizin ®) is recommended as an option for restricted use within NHS Wales for the treatment of bacterial vaginosis only after initial treatment is ineffective or not tolerated, as an alternative option to clindamycin vaginal cream.
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▶Common or very common Increased risk of infection. vulvovaginal disorders ▶Uncommon Haemorrhage. headache. nausea ▶Frequency not known Cystitis. fever
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Does not affect efficacy of latex condoms; however, manufacturer advises avoid use of non-latex condoms and intravaginal devices—no information available.
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Manufacturer advises avoid unless essential—limited information available.
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There can be variation in the licensing of different medicines containing the same drug. Tablet ▶Fluomizin (KoRa Healthcare) Dequalinium chloride 10 mg Fluomizin 10mg vaginal tablets | 6 tablet P £6.95 DT = £6.95 CARBOXYLIC ACIDS
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10 mg once daily for 6 days, inserted
First-line fragment. Read the complete Indications and Dose section above.
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