Drug reference

Desflurane

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1424

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Induction of anaesthesia (but not recommended) ▶BY INHALATION ▶Adult: 4–11 %, to be inhaled through speciﬁcally calibrated vaporiser Maintenance of anaesthesia (in nitrous oxide–oxygen) ▶BY INHALATION ▶Adult: 2–6 %, to be inhaled through a speciﬁcally calibrated vaporiser Maintenance of anaesthesia (in oxygen or oxygen- enriched air) ▶BY INHALATION ▶Adult: 2.5–8.5 %, to be inhaled through a speciﬁcally calibrated vaporiser

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Safety

Interactions

→Appendix 1: volatile halogenated anaesthetics

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Side Effects

▶Common or very common Coagulation disorder. conjunctivitis ▶Uncommon Myalgia. myocardial infarction. myocardial ischaemia. vasodilation ▶Frequency not known Abdominal pain. asthenia. heart failure. hypokalaemia. malaise. metabolic acidosis. pancreatitis acute. shock. skin reactions. ventricular dysfunction. visual acuity decreased

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Pregnancy

May depress neonatal respiration if used during delivery.

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Breast Feeding

Breast-feeding can be resumed as soon as mother has recovered sufﬁciently from anaesthesia.

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Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Inhalation vapour ▶Desflurane (Non-proprietary) Desflurane 1 ml per 1 ml Desflurane volatile liquid | 240 ml P s (Hospital only) eiiii F above

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Dose text by age group

Adult

4–11 %, to be inhaled through speciﬁcally

First-line fragment. Read the complete Indications and Dose section above.

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Adult

2–6 %, to be inhaled through a speciﬁcally

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1424

Adult

2.5–8.5 %, to be inhaled through a speciﬁcally

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1424

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Desflurane

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1424

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

PDF page 1424

Safety

Interactions

→Appendix 1: volatile halogenated anaesthetics

PDF page 1424

Side Effects

PDF page 1424

Pregnancy

May depress neonatal respiration if used during delivery.

PDF page 1424

Breast Feeding

Breast-feeding can be resumed as soon as mother has recovered sufﬁciently from anaesthesia.

PDF page 1424

Dose and formulations

Medicinal Forms

PDF page 1424

Dose text by age group

Adult

4–11 %, to be inhaled through speciﬁcally

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1424

Adult

2–6 %, to be inhaled through a speciﬁcally

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1424

Adult

2.5–8.5 %, to be inhaled through a speciﬁcally

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1424

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.